Kraus P H, Lemke M R, Reichmann H
Department of Neurology, St. Josef-Hospital, University of Bochum, Bochum, Germany.
J Neural Transm (Vienna). 2006 Jul;113(7):845-53. doi: 10.1007/s00702-005-0354-9. Epub 2006 Jan 30.
Since the first description of the disorder which we now call "Parkinson's Disease" (PD) much has changed not only because of new therapeutic possibilities. Initially only the rest tremor was described. Today it is generally accepted that PD can be accompanied by different forms of tremor. Nevertheless the kinetic tremor is hardly examined and no attention is paid to it in clinical rating scales although it can already be found in old published drawings of PD-patients. To date instrumented investigations do not capture the most common kinetic tremor of PD that seems to be frequent under everyday life conditions. In order to assess the significance of kinetic tremor in PD, tremor during a spiral drawing task was investigated in an open study involving 870 patients. The results indicate that a combination of rest, postural and kinetic tremors constitute the most frequent tremor constellation in PD.
自从我们现在称为“帕金森病”（PD）的病症首次被描述以来，不仅因为新的治疗可能性，情况已经发生了很大变化。最初只描述了静止性震颤。如今，人们普遍认为PD可能伴有不同形式的震颤。然而，尽管在早期发表的PD患者绘图中就已发现，但动作性震颤几乎未被研究，在临床评分量表中也未受到关注。迄今为止，仪器化研究并未捕捉到PD最常见的动作性震颤，而这种震颤在日常生活条件下似乎很常见。为了评估动作性震颤在PD中的意义，在一项涉及870名患者的开放性研究中，对螺旋绘图任务期间的震颤进行了调查。结果表明，静止性、姿势性和动作性震颤的组合构成了PD中最常见的震颤组合。
