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通过桡动脉和颈动脉压力波形无创测定的指标的临床应用。

Clinical use of indices determined non-invasively from the radial and carotid pressure waveforms.

作者信息

Adji Audrey, Hirata Kozo, O'Rourke Michael F

机构信息

St Vincent's Clinic, University of New South Wales, Sydney, New South Wales 2010, Australia.

出版信息

Blood Press Monit. 2006 Aug;11(4):215-21. doi: 10.1097/01.mbp.0000218001.50333.b7.

Abstract

OBJECTIVE

To evaluate the clinical use of radial and carotid artery applanation tonometry as an independent supplement to cuff sphygmomanometry.

METHODS

In 44 patients, radial and carotid tonometric pressure recordings were taken at short intervals apart by two persons who had prolonged experience with both. Comparisons were made between directly recorded radial and carotid waveforms and between aortic waves synthesized from both, using SphygmoCor. Focus was on waveform features: time intervals between wavefoot and incisura, denoting ejection duration, between wavefoot and first systolic peak or shoulder T1, and augmentation index - the rise in pressure from this point to systolic peak divided by pulse pressure.

RESULTS

No patient had discomfort with radial tonometry, whereas many found carotid tonometry uncomfortable. Beat-to-beat variability was lower for the radial than carotid site. The device's operator "quality index" was achieved for 78% of radial waveforms but just 20% of carotid waveforms (P<0.05). Interobserver variability was lower for all indices derived from radial, cf. carotid, waveforms. For the two observers combined, there was no difference between aortic indices determined from carotid and radial sites except for T1 (radial-derived 117+ or -17 ms, cf. carotid-derived 103+ or -17 ms, P<0.05), but this did not influence the value of augmentation index (radial-derived 26+ or -13%, cf. carotid-derived 28+ or -14%, P=NS).

CONCLUSION

The present study conforms with most published results, and indicates superiority of radial to carotid tonometry in clinical practice.

摘要

目的

评估桡动脉和颈动脉压平式眼压计作为袖带式血压计独立补充手段的临床应用价值。

方法

选取44例患者,由两位经验丰富的人员在短时间间隔内分别测量桡动脉和颈动脉的眼压计压力记录。使用SphygmoCor对直接记录的桡动脉和颈动脉波形以及由两者合成的主动脉波形进行比较。重点关注波形特征:波峰与切迹之间的时间间隔,代表射血持续时间;波峰与第一个收缩峰或肩部T1之间的时间间隔;以及增强指数——从该点到收缩峰的压力升高除以脉压。

结果

没有患者对桡动脉眼压计测量感到不适,而许多患者觉得颈动脉眼压计测量不舒服。桡动脉部位的逐搏变异性低于颈动脉部位。该设备的操作员“质量指数”在78%的桡动脉波形中达到,但在颈动脉波形中仅为20%(P<0.05)。所有源自桡动脉波形的指标的观察者间变异性均低于颈动脉波形。对于两位观察者的数据合并后,除了T1(源自桡动脉的为117±17毫秒,源自颈动脉的为103±17毫秒,P<0.05)外,由颈动脉和桡动脉部位确定的主动脉指标之间没有差异,但这并不影响增强指数的值(源自桡动脉的为26±13%,源自颈动脉的为28±14%,P=无显著差异)。

结论

本研究与大多数已发表的结果一致,并表明在临床实践中桡动脉眼压计优于颈动脉眼压计。

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