Worthington Nancy, Markham Piper Tinka, Galea Sandro, Rosenthal David
Lower East Side Harm Reduction Center, New York, NY 10002, USA.
Harm Reduct J. 2006 Jul 5;3:19. doi: 10.1186/1477-7517-3-19.
Drug-induced and drug-related deaths have been increasing for the past decade throughout the US. In NYC, drug overdose accounts for nearly 900 deaths per year, a figure that exceeds the number of deaths each year from homicide. Naloxone, a highly effective opiate antagonist, has for decades been used by doctors and paramedics during emergency resuscitation after an opiate overdose. Following the lead of programs in Europe and the US who have successfully distributed take-home naloxone, the Overdose Prevention and Reversal Program at the Lower East Side Harm Reduction Center (LESHRC) has started providing a similar resource for opiate users in NYC. Participants in the program receive a prescription for two doses of naloxone, with refills as needed, and comprehensive training to reduce overdose risk, administer naloxone, perform rescue breathing, and call 911. As of September 2005, 204 participants have received naloxone and been trained, and 40 have revived an overdosing friend or family member. While naloxone accessibility stands as a proven life-saving measure, some opiates users at LESHRC have expressed only minimal interest in naloxone use, due to past experiences and common misconceptions.
In order to improve the naloxone distribution program two focus groups were conducted in December 2004 with 13 opiate users at LESHRC to examine knowledge about overdose and overdose prevention. The focus groups assessed participants' (i) experiences with overdose response, specifically naloxone (ii) understanding and perceptions of naloxone, (iii) comfort level with naloxone administration and (iv) feedback about increasing the visibility and desirability of the naloxone distribution program.
Analyses suggest that there is both support for and resistance to take-home naloxone, marked by enthusiasm for its potential role in reviving an overdosing individual, numerous misconceptions and negative views of its impact and use.
Focus group results will be used to increase participation in the program and reshape perceptions about naloxone among opiate users, also targeting those already prescribed naloxone to increase their comfort using it. Since NYC is advancing toward a citywide naloxone distribution program, the LESHRC program will play an important role in establishing protocol for effective and wide-reaching naloxone availability.
在过去十年中,美国各地与药物相关的死亡人数一直在增加。在纽约市,药物过量每年导致近900人死亡,这一数字超过了每年因凶杀案死亡的人数。纳洛酮是一种高效的阿片类拮抗剂,几十年来一直被医生和护理人员用于阿片类药物过量后的紧急复苏。效仿欧洲和美国成功分发可带回家使用的纳洛酮的项目,下东区减少伤害中心(LESHRC)的过量预防与逆转项目已开始为纽约市的阿片类药物使用者提供类似资源。该项目的参与者会收到两剂纳洛酮的处方,并可根据需要进行续方,同时还会接受全面培训,以降低过量风险、使用纳洛酮、进行人工呼吸以及拨打911。截至2005年9月,已有204名参与者领取了纳洛酮并接受了培训,其中40人救活了一名药物过量的朋友或家人。虽然获取纳洛酮是一项经证实的挽救生命的措施,但由于过去的经历和常见的误解,LESHRC的一些阿片类药物使用者对使用纳洛酮的兴趣不大。
为了改进纳洛酮分发项目,2004年12月对LESHRC的13名阿片类药物使用者进行了两个焦点小组访谈,以了解他们对过量用药及过量预防的知识。焦点小组评估了参与者:(i)对过量用药反应的经历,特别是对纳洛酮的经历;(ii)对纳洛酮的理解和看法;(iii)使用纳洛酮的舒适度;(iv)关于提高纳洛酮分发项目的知名度和吸引力的反馈。
分析表明,对于可带回家使用的纳洛酮,既有支持也有抵触,一方面对其在救活药物过量者方面的潜在作用充满热情,另一方面对其影响和使用存在诸多误解和负面看法。
焦点小组的结果将用于提高该项目的参与度,并重塑阿片类药物使用者对纳洛酮的看法,同时针对那些已经开具纳洛酮处方的人,提高他们使用纳洛酮的舒适度。由于纽约市正在推进全市范围的纳洛酮分发项目,LESHRC项目将在制定有效且广泛可用的纳洛酮方案方面发挥重要作用。