Ouattara H, Siransy-Bogui L, Fretz C, Diane K M, Konate S, Koidio A, Minga K A, Hyda J, Koffi-Abe N, Offoumou A M, Abissey S
Service d'endocrinologie et biologie de la reproduction, UFR biosciences, université de Cocody, 14 BP 840 Abidjan 14, Abidjan, Ivory Coast.
Transfus Clin Biol. 2006 Oct;13(4):242-5. doi: 10.1016/j.tracli.2006.03.015. Epub 2006 Jul 5.
The assessment of the viral residual risk from blood products is an assessment indicator of the quality management system and of the availability process of these products. Assessments of HIV, HBV and HCV viruses transmission risks through blood transfusion are calculated after the setting of a quality approach at the Abidjan NBTC. The method used estimates the risk of a donation made during a period immunologically silent. The residual risks for HIV, HBV, and HCV viruses have been estimated by multiplying the incidence rate for 100,000 people per year by the respective durations of the serological windows. The data received from the Abidjan Center's information processing system (Progesa 4.4d of MAK SYSTEM) go from 2002 to 2004 period. The residual risks are 1/5780 donations for HIV and 1/406 donations for the HCV, then 1/383 donations for the HBV. The residual risk for the HIV is almost four times reduced compared to that of 1997. The results show not only the importance of the transmission risk of HIV, HBV and HCV viruses through blood products, but also the necessity to set a quality management system in endemic countries of Sub-Saharan Africa.
对血液制品病毒残留风险的评估是质量管理体系以及这些产品供应过程的一项评估指标。在阿比让国家输血中心制定质量方针后，计算通过输血传播艾滋病毒、乙肝病毒和丙肝病毒的风险。所采用的方法估计了在免疫静默期进行献血的风险。艾滋病毒、乙肝病毒和丙肝病毒的残留风险是通过将每年每10万人的发病率乘以各自血清学窗口期的时长来估算的。从阿比让中心信息处理系统（MAK SYSTEM的Progesa 4.4d）获得的数据涵盖2002年至2004年期间。艾滋病毒的残留风险为每5780次献血中有1次，丙肝病毒为每406次献血中有1次，乙肝病毒为每383次献血中有1次。与1997年相比，艾滋病毒的残留风险几乎降低了四倍。结果不仅表明了通过血液制品传播艾滋病毒、乙肝病毒和丙肝病毒的风险的重要性，还表明了在撒哈拉以南非洲流行国家建立质量管理体系的必要性。
