Antifungal anthraquinones from Saprosma fragrans.
作者信息
Singh D N, Verma N, Raghuwanshi S, Shukla P K, Kulshreshtha D K
机构信息
Medicinal and Process Chemistry Division, Central Drug Research Institute, Chattar Manzil Palace, Lucknow, India.
出版信息
Bioorg Med Chem Lett. 2006 Sep 1;16(17):4512-4. doi: 10.1016/j.bmcl.2006.06.027. Epub 2006 Jul 7.
Abstract
A new 3,4-dihydroxy-1-methoxy anthraquinone-2-corboxaldehyde (1) together with a known anthraquinone, damnacanthal (2), were isolated from the chloroform fraction of the aerial part (whole plant without root) of Saprosma fragrans. The isolated anthraquinones (1) and (2) were found to exhibit antifungal activity against Trichophyton mentagrophytes and Sporitrichum schenckii. Their structures were established by chemical and spectral analysis.
摘要
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