Kalix P, Brenneisen R, Koelbing U, Fisch H U, Mathys K
Psychiatrische Universitäts-Poliklinik, Bern.
Schweiz Med Wochenschr. 1991 Oct 26;121(43):1561-6.
Because of their stimulating effect, leaves of the khat bush are chewed in several East African countries and in Yemen. Since only fresh leaves are active, this habit is almost unknown outside the regions where the plant grows. Recently, however, khat has made its appearance in the United States and in several European countries, while an import permit has been requested in Switzerland. These are reasons for making the practitioner familiar with the effects of this drug. During the last fifteen years, knowledge of khat and its constituents has made substantial progress. Today, the alkaloid cathinone is regarded as the main active principle of this drug, and this substance is held to be a natural amphetamine. This article summarizes knowledge of the pharmacology of khat.
由于其刺激作用,巧茶灌木的叶子在几个东非国家和也门被咀嚼。由于只有新鲜叶子才有活性,这种习惯在该植物生长地区以外几乎无人知晓。然而,最近巧茶已在美国和几个欧洲国家出现,而瑞士已申请进口许可。这些都是让从业者熟悉这种药物作用的原因。在过去的十五年里,对巧茶及其成分的认识有了长足的进步。如今,生物碱卡西酮被认为是这种药物的主要活性成分,这种物质被认为是一种天然安非他命。本文总结了巧茶的药理学知识。