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副流感病毒在流行传播期间的自然种群变异性研究。

Studies of natural population variability of parainfluenza viruses during their epidemic circulation.

作者信息

Yurlova T I, Sverkunova M V, Furaeva V A, Sukhinin V P, Shitikova G S, Fedová D, Kunzová L

机构信息

USSR Research Institute of Influenza of the USSR Ministry of Health, Leningrad.

出版信息

Acta Virol. 1991 Jan;35(1):64-70.

PMID:1683117
Abstract

The population of circulating serotype 3 parainfluenza virus strains isolated in different years proved to be sufficiently polymorphic concerning its antigenic and biological features as well as their virulence for newborn hamsters. The highly virulent strain population appeared to have an antigenic pattern different from that of the prototype strain. The epidemic caused by it in groups of school and preschool children was more intensive as compared to that induced by avirulent strains population.

摘要

事实证明,不同年份分离出的3型副流感病毒株群体在抗原和生物学特性以及对新生仓鼠的毒力方面具有足够的多态性。高毒株群体的抗原模式似乎与原型毒株不同。与无毒株群体引发的疫情相比,它在学龄儿童和学龄前儿童群体中引发的疫情更为严重。

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