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小脑蚓部葡萄糖利用与眼肌阵挛

Glucose utilization in the inferior cerebellar vermis and ocular myoclonus.

作者信息

Yakushiji Y, Otsubo R, Hayashi T, Fukuchi K, Yamada N, Hasegawa Y, Minematsu K

机构信息

Cerebrovascular Division, Department of Medicine, National Cardiovascular Center, Osaka, Japan.

出版信息

Neurology. 2006 Jul 11;67(1):131-3. doi: 10.1212/01.wnl.0000223837.52895.2e.

DOI:10.1212/01.wnl.0000223837.52895.2e
PMID:16832091
Abstract

In a patient with symptomatic ocular myoclonus, the authors observed the regional cerebral metabolic rate of glucose use (rCMRGlu) before and after successful treatment with clonazepam. Even after the symptoms resolved, the rCMRGlu in the hypertrophic olive increased persistently, whereas that in the inferior cerebellar vermis contralateral to the hypertrophic olive decreased. The inferior cerebellar vermis, belonging to the vestibulocerebellar system, may be associated with the generation of symptomatic ocular myoclonus.

摘要

在一名有症状性眼球肌阵挛的患者中,作者观察了使用氯硝西泮成功治疗前后的局部脑葡萄糖代谢率(rCMRGlu)。即使症状缓解后,肥大橄榄核的rCMRGlu仍持续升高,而与肥大橄榄核相对侧的小脑下蚓部的rCMRGlu则降低。属于前庭小脑系统的小脑下蚓部可能与症状性眼球肌阵挛的产生有关。

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Brain. 2010 Mar;133(Pt 3):923-40. doi: 10.1093/brain/awp323. Epub 2010 Jan 15.