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伴有异常单光子发射计算机断层扫描成像的眼阵挛-肌阵挛综合征

Opsoclonus-myoclonus syndrome with abnormal single photon emission computed tomography imaging.

作者信息

Oguro K, Kobayashi J, Aiba H, Hojo H

机构信息

Division of Child Neurology, Shizuoka Children's Hospital, Japan.

出版信息

Pediatr Neurol. 1997 May;16(4):334-6. doi: 10.1016/s0887-8994(97)00031-3.

DOI:10.1016/s0887-8994(97)00031-3
PMID:9258970
Abstract

The single photon emission computed tomography (SPECT) findings in 2 patients with opsoclonus-myoclonus syndrome (OMS) who had similar symptoms in the acute stage of the disease are described. In 1 patient with encephalitis, SPECT showed increased blood flow in most of the cerebellum; the highest accumulation of the radiotracer was found in the cerebellar vermis and neighboring structures. These changes disappeared with clinical improvement. In the other patient with chronic OMS, SPECT demonstrated hypoperfusion in most of the cerebellum. Our results suggest that the cerebellum, particularly its middle portion, is involved in the generation of OMS. SPECt is a useful method that enables us to detect in vivo functional impairment in patients with OMS.

摘要

描述了2例在疾病急性期有相似症状的眼阵挛-肌阵挛综合征(OMS)患者的单光子发射计算机断层扫描(SPECT)结果。1例患有脑炎的患者,SPECT显示小脑大部分区域血流增加;放射性示踪剂的最高积聚出现在小脑蚓部和邻近结构。这些变化随着临床症状的改善而消失。另1例患有慢性OMS的患者,SPECT显示小脑大部分区域灌注不足。我们的结果表明,小脑,特别是其中部,参与了OMS的发生。SPECT是一种有用的方法,能使我们检测OMS患者体内的功能损害。

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