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抗癫痫药物撤药后海马异常与癫痫复发

Hippocampal abnormalities and seizure recurrence after antiepileptic drug withdrawal.

作者信息

Cardoso T A M, Coan A C, Kobayashi E, Guerreiro C A M, Li L M, Cendes F

机构信息

Department of Neurology, FCM, State University of Campinas-UNICAMP, Brazil.

出版信息

Neurology. 2006 Jul 11;67(1):134-6. doi: 10.1212/01.wnl.0000223350.08394.06.

DOI:10.1212/01.wnl.0000223350.08394.06
PMID:16832092
Abstract

The authors performed hippocampal volumetry and T2 relaxometry in 84 consecutive patients with partial epilepsy from a protocol for antiepileptic drug (AED) withdrawal after at least 2 years of seizure control. Seizure recurrence after AED withdrawal was more frequent among patients with hippocampal atrophy and abnormal hippocampal T2 signal.

摘要

作者对84例连续的部分性癫痫患者进行了海马体积测量和T2弛豫测量,这些患者来自一项在癫痫发作控制至少2年后停用抗癫痫药物(AED)的方案。在有海马萎缩和海马T2信号异常的患者中,停用AED后癫痫复发更为频繁。

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