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Consequences of antiepileptic drug withdrawal: a randomized, double-blind study (Akershus Study).抗癫痫药物撤药的后果:一项随机双盲研究(阿克什胡斯研究)
Epilepsia. 2008 Mar;49(3):455-63. doi: 10.1111/j.1528-1167.2007.01323.x. Epub 2007 Sep 19.
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Hippocampal abnormalities and seizure recurrence after antiepileptic drug withdrawal.抗癫痫药物撤药后海马异常与癫痫复发
Neurology. 2006 Jul 11;67(1):134-6. doi: 10.1212/01.wnl.0000223350.08394.06.
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Rapid versus slow withdrawal of antiepileptic drugs.抗癫痫药物的快速撤药与缓慢撤药
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Should antiepileptic drugs be withdrawn in seizure-free patients?癫痫发作已控制的患者是否应停用抗癫痫药物?
CNS Drugs. 2004;18(4):201-12. doi: 10.2165/00023210-200418040-00001.
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Early versus late antiepileptic drug withdrawal for people with epilepsy in remission.癫痫缓解期患者早期与晚期停用抗癫痫药物的比较。
Cochrane Database Syst Rev. 2001(3):CD001902. doi: 10.1002/14651858.CD001902.
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Early identification of refractory epilepsy.难治性癫痫的早期识别。
N Engl J Med. 2000 Feb 3;342(5):314-9. doi: 10.1056/NEJM200002033420503.
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Does withdrawal of different antiepileptic drugs have different effects on seizure recurrence? Further results from the MRC Antiepileptic Drug Withdrawal Study.停用不同的抗癫痫药物对癫痫复发的影响是否不同?医学研究委员会抗癫痫药物撤药研究的进一步结果。
Brain. 1999 Mar;122 ( Pt 3):441-8. doi: 10.1093/brain/122.3.441.
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Prognostic index for recurrence of seizures after remission of epilepsy. Medical Research Council Antiepileptic Drug Withdrawal Study Group.癫痫缓解后癫痫发作复发的预后指数。医学研究委员会抗癫痫药物撤药研究组。
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Relapse following discontinuation of antiepileptic drugs: a meta-analysis.抗癫痫药物停药后的复发:一项荟萃分析。
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Randomised study of antiepileptic drug withdrawal in patients in remission. Medical Research Council Antiepileptic Drug Withdrawal Study Group.缓解期患者抗癫痫药物撤药的随机研究。医学研究委员会抗癫痫药物撤药研究组。
Lancet. 1991 May 18;337(8751):1175-80.

To stop or not to stop the AED?

作者信息

Meador Kimford J

出版信息

Epilepsy Curr. 2008 Jul-Aug;8(4):90-1. doi: 10.1111/j.1535-7511.2008.00250.x.

DOI:10.1111/j.1535-7511.2008.00250.x
PMID:18596871
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2442147/
Abstract
摘要