补体成分6（C6）和9（C9）的人类基因在5号染色体上紧密连锁。
The human genes for complement components 6 (C6) and 9 (C9) are closely linked on chromosome 5.
作者信息
Rogne S, Myklebost O, Olving J H, Kyrkjebø H T, Jonassen R, Olaisen B, Gedde-Dahl T
机构信息
Department of Animal Science, Agricultural University, Norway.
出版信息
J Med Genet. 1991 Sep;28(9):587-90. doi: 10.1136/jmg.28.9.587.
Abstract
We have used a cDNA probe for human complement component 9 (C9), which detects three DNA polymorphisms, to analyse the inheritance of C9 in families informative for C6 protein variants. We found that these genes are closely linked with a lod score of 9.28 at recombination fraction 0.00. There is not indication of allelic association.
摘要
我们使用了一种针对人补体成分9（C9）的cDNA探针，该探针可检测到三种DNA多态性，以分析C6蛋白变体信息丰富的家族中C9的遗传情况。我们发现这些基因紧密连锁，在重组率为0.00时，连锁值为9.28。没有等位基因关联的迹象。
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