Deb Subrato, Yun Joon, Burton Nelson, Omron Edward, Thurber John, Nathan Steven D
Department of Cardiothoracic Surgery, National Naval Medical Center, Bethesda, MD, USA.
Chest. 2006 Jul;130(1):214-7. doi: 10.1378/chest.130.1.214.
Prior to the advent of effective medical therapies, the only treatment option for patients with idiopathic pulmonary arterial hypertension (IPAH) was lung transplantation. We present the case of a woman who underwent single-lung transplantation for the treatment of IPAH > 10 years ago in whom chronic rejection developed. Despite complete obliteration of the allograft, it was noted that her PA pressure levels had almost normalized. Therefore, an allograft pneumonectomy was performed. To our knowledge, this is the first reported case of the regression of pulmonary vascular disease following lung transplantation with subsequent successful removal of the allograft.
在有效的药物治疗出现之前，特发性肺动脉高压（IPAH）患者唯一的治疗选择是肺移植。我们报告一例10多年前因IPAH接受单肺移植的女性患者，该患者发生了慢性排斥反应。尽管移植肺完全闭塞，但发现她的肺动脉压力水平几乎已恢复正常。因此，实施了移植肺切除术。据我们所知，这是首例报道的肺移植后肺血管疾病消退且随后成功切除移植肺的病例。
