Mulligan T, Frick M F, Zuraw Q C, Stemhagen A, McWhirter C
Division of Geriatrics, Malcom Randall VAMC GRECC and University of Florida, Gainesville, FL 32608, USA.
Int J Clin Pract. 2006 Jul;60(7):762-9. doi: 10.1111/j.1742-1241.2006.00992.x.
The Hypogonadism in Males study estimated the prevalence of hypogonadism [total testosterone (TT) < 300 ng/dl] in men aged > or = 45 years visiting primary care practices in the United States. A blood sample was obtained between 8 am and noon and assayed for TT, free testosterone (FT) and bioavailable testosterone (BAT). Common symptoms of hypogonadism, comorbid conditions, demographics and reason for visit were recorded. Of 2162 patients, 836 were hypogonadal, with 80 receiving testosterone. Crude prevalence rate of hypogonadism was 38.7%. Similar trends were observed for FT and BAT. Among men not receiving testosterone, 756 (36.3%) were hypogonadal; odds ratios for having hypogonadism were significantly higher in men with hypertension (1.84), hyperlipidaemia (1.47), diabetes (2.09), obesity (2.38), prostate disease (1.29) and asthma or chronic obstructive pulmonary disease (1.40) than in men without these conditions. The prevalence of hypogonadism was 38.7% in men aged > or = 45 years presenting to primary care offices.
男性性腺功能减退研究估算了美国45岁及以上前往初级保健机构就诊男性的性腺功能减退（总睾酮[TT]<300 ng/dl）患病率。上午8点至中午采集血样，检测TT、游离睾酮（FT）和生物可利用睾酮（BAT）。记录性腺功能减退的常见症状、合并症、人口统计学特征和就诊原因。在2162例患者中，836例性腺功能减退，80例接受睾酮治疗。性腺功能减退的粗患病率为38.7%。FT和BAT也观察到类似趋势。在未接受睾酮治疗的男性中，756例（36.3%）性腺功能减退；患有高血压（比值比1.84）、高脂血症（1.47）、糖尿病（2.09）、肥胖（2.38）、前列腺疾病（1.29）以及哮喘或慢性阻塞性肺疾病（1.40）的男性患性腺功能减退的比值比显著高于无这些疾病的男性。45岁及以上前往初级保健机构就诊男性中性腺功能减退的患病率为38.7%。
