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创伤后应激障碍的自然病程:对土耳其地震幸存者的一项为期20个月的前瞻性研究。

Natural course of posttraumatic stress disorder: a 20-month prospective study of Turkish earthquake survivors.

作者信息

Karamustafalioglu Oguz K, Zohar Joseph, Güveli Mustafa, Gal Gilad, Bakim Bahadir, Fostick Leah, Karamustafalioglu Nesrin, Sasson Yehuda

机构信息

Department of Psychiatry, Sisli Eftal Teaching and Research Hospital, Istanbul, Turkey.

出版信息

J Clin Psychiatry. 2006 Jun;67(6):882-9. doi: 10.4088/jcp.v67n0604.

Abstract

OBJECTIVE

A 20-month prospective follow-up of survivors of the severe earthquake in Turkey in 1999 examined the natural course of posttraumatic stress disorder (PTSD) and the contribution of different symptom clusters to the emergence of PTSD.

METHOD

Subjects were randomly sampled in a suburb of Istanbul that was severely affected by the earthquake. A total of 464 adults were assessed with a self-report instrument for PTSD symptoms on 3 consecutive surveys that were administered 1 to 3, 6 to 10, and 18 to 20 months following the earthquake.

RESULTS

The prevalence of PTSD was 30.2% on the first survey and decreased to 26.9% and 10.6% on the second and third surveys, respectively. Female subjects showed initially higher (34.8%) PTSD rates compared with male subjects (19.1%). However, gender differences disappeared by the time of the third survey due to high spontaneous remission rates in female subjects. Low levels of chronic and delayed-onset PTSD were observed. A major contribution of the avoidance symptoms to PTSD diagnosis was identified by statistical analysis.

CONCLUSIONS

Initial PTSD following an earthquake may be as prevalent as in other natural disasters, but high rates of spontaneous remission lead to low prevalence 1.5 years following the earthquake. Initial avoidance characteristics play a major role in the emergence of PTSD.

摘要

目的

对1999年土耳其大地震幸存者进行为期20个月的前瞻性随访,以研究创伤后应激障碍(PTSD)的自然病程以及不同症状群对PTSD发生的影响。

方法

在伊斯坦布尔一个受地震严重影响的郊区进行随机抽样。共有464名成年人在地震后的1至3个月、6至10个月以及18至20个月这三个连续阶段接受了关于PTSD症状的自我报告工具评估。

结果

在第一次调查中,PTSD的患病率为30.2%,在第二次和第三次调查中分别降至26.9%和10.6%。女性受试者最初的PTSD发生率(34.8%)高于男性受试者(19.1%)。然而,由于女性受试者的自发缓解率较高,到第三次调查时性别差异消失。观察到慢性和延迟性PTSD的水平较低。通过统计分析确定了回避症状对PTSD诊断的主要影响。

结论

地震后的初始PTSD患病率可能与其他自然灾害中的患病率一样高,但高自发缓解率导致地震1.5年后患病率较低。初始回避特征在PTSD的发生中起主要作用。

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