van Gelder Boukje Maria, Tijhuis Marja, Kalmijn Sandra, Giampaoli Simona, Nissinen Aulikki, Kromhout Daan
National Institute for Public Health and the Environment, Centre for Prevention and Health Services Research, PO Box 1, Internal Postal Code 101, 3720 BA, Bilthoven, the Netherlands.
J Gerontol B Psychol Sci Soc Sci. 2006 Jul;61(4):P213-9. doi: 10.1093/geronb/61.4.p213.
We investigate the association between marital status and living situation (over 5 years) on 10-year subsequent cognitive decline. The study population consisted of 1,042 men aged 70-89 years in 1990, who participated in the longitudinal Finland, Italy, the Netherlands Elderly (known as FINE) Study. We measured cognition by using the Mini-Mental State Examination, and we assessed marital status (married vs unmarried) and living situation (living with others vs living alone) with a standardized questionnaire. We performed repeated measurement analyses and made adjustments for age, education, country, smoking, alcohol, chronic diseases, marital status or living situation, and baseline cognition. Men who lost a partner, who were unmarried, who started to live alone, or who lived alone during the 5-year period had at least a two times stronger subsequent cognitive decline compared with men who were married or who lived with someone in those years.
我们研究了婚姻状况和生活状况（超过5年）与10年后认知能力下降之间的关联。研究人群包括1990年年龄在70 - 89岁的1042名男性，他们参与了芬兰、意大利、荷兰老年人纵向研究（简称FINE研究）。我们使用简易精神状态检查表来测量认知能力，并用标准化问卷评估婚姻状况（已婚与未婚）和生活状况（与他人同住与独居）。我们进行了重复测量分析，并对年龄、教育程度、国家、吸烟、饮酒、慢性病、婚姻状况或生活状况以及基线认知进行了调整。在这5年期间失去伴侣、未婚、开始独居或一直独居的男性，其随后的认知能力下降程度至少是那些在这些年里已婚或与他人同住男性的两倍。
