Fu Wen-wei, Hou Wen-bin, Dou De-qiang, Hua Hui-ming, Gui Mao-hua, Fu Rui, Chen Ying-jie, Pei Yue-hu
School of Traditional Chinese Material Medica, Shenyang Pharmaceutical University, China.
Yao Xue Xue Bao. 2006 Apr;41(4):358-60.
To isolate triterpene saponins of polygalacic acid type from the roots of Platycodon grandiflorum (Jacq.) A. DC and to identify their structures.
The compounds were separated by means of extraction, chromatography on silica gel, MPLC and HPLC, and their structures were elucidated on the basis of spectral analyses (FAB-MS, IR, 1H NMR, 13C NMR etc.).
Three triterpene saponins were isolated from the roots of Platycodon grandiflorum. They were identified as 3-O-beta-D-laminaribiosyl polygalacic acid (I), 3-O-beta-D-glucopyranosyl polygalacic acid (II), polygalacin D (III), separately.
Compound I is a new compound, compounds II, III are known triterpene saponins. The compound I and II were isolated from the plant for the first time, which is also the monodesmoside from the plant for the first time.
从桔梗（Platycodon grandiflorum (Jacq.) A. DC）根中分离聚半乳糖醛酸型三萜皂苷并鉴定其结构。
通过提取、硅胶柱色谱、MPLC和HPLC分离化合物，并基于光谱分析（FAB-MS、IR、1H NMR、13C NMR等）阐明其结构。
从桔梗根中分离出三种三萜皂苷。它们分别被鉴定为3-O-β-D-层叠二糖基聚半乳糖醛酸（I）、3-O-β-D-吡喃葡萄糖基聚半乳糖醛酸（II）、聚半乳糖醛酸D（III）。
化合物I为新化合物，化合物II、III为已知三萜皂苷。化合物I和II首次从该植物中分离得到，也是首次从该植物中得到的单糖链皂苷。
