Bonaros Nikolaos, Schachner Thomas, Oehlinger Armin, Ruetzler Elisabeth, Kolbitsch Christian, Dichtl Wolfgang, Mueller Silvana, Laufer Guenther, Bonatti Johannes
Department of Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria.
Ann Thorac Surg. 2006 Aug;82(2):687-93. doi: 10.1016/j.athoracsur.2006.03.024.
Remote access perfusion and robotics have enabled totally endoscopic closure of atrial septal defect and patent foramen ovale. The aim of this study was to address learning curve issues of totally endoscopic atrial septal defect repair on the basis of a single-center experience and to investigate whether long cardiopulmonary bypass and aortic occlusion times influence intraoperative and postoperative outcomes.
Seventeen patients (median age, 35 years; range, 16 to 55 years) underwent totally endoscopic atrial septal defect repair using remote access perfusion and robotic technology (da Vinci telemanipulation system). Learning curves were assessed by means of regression analysis with logarithmic curve fit. The effect of operative variables on clinical outcome was analyzed by linear regression using the Spearman's rho coefficient.
No operative mortality or serious surgical complications were observed. No residual shunt was detected at intraoperative or postoperative echocardiography. Significant learning curves were noted for total operative time: y(min) = 406 - 49 ln(x) (r2 = 0.725; p = 0.002); cardiopulmonary bypass time: y(min) = 225 - 42 ln(x) (r2 = 0.699; p = 0.003); and aortic occlusion time: y(min) = 117 - 25 ln(x) (r2 = 0.517; p = 0.04), x = number of procedures. Median ventilation time, intensive care unit stay, and hospital length of stay were 7 hours (range, 2 to 19 hours), 26 hours (range, 15 to 120 hours), and 8 days (range, 5 to 14 days), respectively. No correlation was detected between cardiopulmonary bypass time and intubation time (r2 = 0.283; p = 0.326), intensive care unit stay (r2 = -0.138; p = 0.639), or total length of stay (r2 = 0.013; p = 0.962).
Totally endoscopic atrial septal defect repair can be performed safely, and learning curves for operative times are steep. Longer cardiopulmonary bypass times had no negative impact on intraoperative and postoperative outcome.
远程接入灌注和机器人技术已实现房间隔缺损和卵圆孔未闭的完全内镜闭合。本研究的目的是基于单中心经验探讨完全内镜房间隔缺损修复的学习曲线问题,并研究较长的体外循环和主动脉阻断时间是否会影响术中和术后结果。
17例患者(中位年龄35岁;范围16至55岁)接受了使用远程接入灌注和机器人技术(达芬奇远程操作手术系统)的完全内镜房间隔缺损修复术。通过对数曲线拟合的回归分析评估学习曲线。使用Spearman等级相关系数通过线性回归分析手术变量对临床结果的影响。
未观察到手术死亡或严重手术并发症。术中或术后超声心动图未检测到残余分流。观察到总手术时间的显著学习曲线:y(分钟)=406 - 49 ln(x)(r2 = 0.725;p = 0.002);体外循环时间:y(分钟)=225 - 42 ln(x)(r2 = 0.699;p = 0.003);以及主动脉阻断时间:y(分钟)=117 - 25 ln(x)(r2 = 0.517;p = 0.04),x =手术例数。中位通气时间、重症监护病房停留时间和住院时间分别为7小时(范围2至19小时)、26小时(范围15至120小时)和8天(范围5至14天)。未检测到体外循环时间与插管时间(r2 = 0.283;p = 0.326)、重症监护病房停留时间(r2 = -0.138;p = 0.639)或总住院时间(r2 = 0.013;p = 0.962)之间存在相关性。
完全内镜房间隔缺损修复术可安全进行,手术时间的学习曲线较陡。较长的体外循环时间对术中和术后结果无负面影响。