Mizia-Stec Katarzyna, Gasior Zbigniew, Duława Jan, Janowska Mirosława, Pysz Piotr, Mizia Magdalena
Department of Cardiology, Silesian University, Faculty of Medicine, Ziołowa Street 45/47, 40-635 Katowice, Poland.
Heart Vessels. 2006 Jul;21(4):263-6. doi: 10.1007/s00380-005-0880-2.
We present and discuss the case of a 26-year-old man suffering from Churg-Strauss syndrome (CSS). In our patient the disease severely affected both the heart and the lungs. Left ventricular dysfunction and intracardiac thrombosis, probably secondary to the cardiotoxic effect of eosinophils, were revealed by echocardiography. The risk of thrombosis was additionally increased by the coexistence of the factor V Leiden gene mutation. An opportunely established diagnosis allowed institution of an appropriate pharmacotherapy and subsequently to obtain a significant abatement of the clinical symptoms as well as the laboratory manifestations of the disease.
我们报告并讨论了一例26岁患有Churg-Strauss综合征（CSS）的男性病例。在我们的患者中，该疾病严重影响了心脏和肺部。超声心动图显示左心室功能障碍和心内血栓形成，可能继发于嗜酸性粒细胞的心脏毒性作用。因子V Leiden基因突变的并存进一步增加了血栓形成的风险。及时确立的诊断使得能够实施适当的药物治疗，并随后使疾病的临床症状以及实验室表现得到显著缓解。
