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变应性肉芽肿性血管炎致心脏肿块并右心室阻塞。

Churg-strauss syndrome presenting with cardiac mass and right ventricular obstruction.

机构信息

First Department of Medicine, Division of Cardiology, University Hospital of Jena. Germany

出版信息

Clin Cardiol. 2009 Dec;32(12):E77-9. doi: 10.1002/clc.20595.

DOI:10.1002/clc.20595
PMID:20014201
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6652959/
Abstract

A 57-year-old woman presenting with asthma, hypereosinophilia, and generalized unspecific symptoms was diagnosed with Churg-Strauss syndrome. Echocardiography revealed a cardiac mass obliterating the right ventricle and severely impaired left ventricular function, which were caused by endomyocardial fibrosis. Cortisone and cyclophosphamide therapy resulted in amelioration of left ventricular function and significant size reduction of the right ventricular mass.

摘要

一位 57 岁女性因哮喘、嗜酸性粒细胞增多和全身非特异性症状就诊，被诊断为 Churg-Strauss 综合征。超声心动图显示心肌内肿块使右心室闭塞并严重损害左心室功能，这是由心内膜心肌纤维化引起的。皮质激素和环磷酰胺治疗使左心室功能得到改善，右心室肿块的大小显著缩小。

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Churg-strauss syndrome presenting with cardiac mass and right ventricular obstruction.变应性肉芽肿性血管炎致心脏肿块并右心室阻塞。
Clin Cardiol. 2009 Dec;32(12):E77-9. doi: 10.1002/clc.20595.
2
[Left ventricular dysfunction in Churg-Strauss syndrome].[变应性肉芽肿性血管炎中的左心室功能障碍]
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3
Endomyocardial fibrosis in Churg-Strauss syndrome assessed by cardiac magnetic resonance imaging.通过心脏磁共振成像评估的Churg-Strauss综合征中的心内膜心肌纤维化。
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[MR imaging of endomyocardial fibrosis representing cardiac involvement in Churg-Strauss syndrome].
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[MR tomography presentation of endomyocardial fibrosis as an expression of cardiac involvement in Churg-Strauss syndrome].[心肌内膜纤维化的磁共振断层扫描表现作为Churg-Strauss综合征心脏受累的一种表现]
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Churg-Strauss syndrome presenting as an abdominal mass in a non-asthmatic child.以腹部肿块为表现的非哮喘儿童的变应性肉芽肿性血管炎。
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引用本文的文献

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Cardiac Mass and Cerebrovascular Accident as Primary Manifestations of Churg-Strauss Syndrome.心脏肿块和脑血管意外作为变应性肉芽肿性血管炎的主要表现。
Arch Iran Med. 2023 Nov 1;26(11):662-664. doi: 10.34172/aim.2023.97.
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Churg-Strauss vasculitis presenting with steroid-responsive left ventricular cardiac mass.以类固醇反应性左心室心脏肿块为表现的变应性肉芽肿性血管炎。
BMJ Case Rep. 2018 Oct 17;2018:bcr-2018-226052. doi: 10.1136/bcr-2018-226052.
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Eosinophilic Granulomatosis with Polyangiitis (EGPA) with an Unusual Manifestation of Mid-Ventricular Obstruction Caused by Endocardial Thrombus.伴有心内膜血栓导致的心室中部梗阻这一不寻常表现的嗜酸性肉芽肿性多血管炎（EGPA）。
Am J Case Rep. 2018 Oct 8;19:1197-1203. doi: 10.12659/AJCR.910861.
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Antiproteinase 3 Positive Eosinophilic Granulomatosis with Polyangiitis Presenting with Heart Failure and Intraventricular Thrombosis.抗蛋白酶3阳性嗜酸性肉芽肿伴多血管炎合并心力衰竭及心室内血栓形成。
Case Rep Rheumatol. 2017;2017:2908185. doi: 10.1155/2017/2908185. Epub 2017 Jan 29.
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ANCA-negative eosinophilic granulomatosis with polyangitis (EGPA) manifesting as a large intracardiac thrombus and glomerulonephritis with angionecrosis.抗中性粒细胞胞浆抗体阴性的嗜酸性肉芽肿性多血管炎（EGPA）表现为巨大心内血栓和伴有血管坏死的肾小球肾炎。
BMJ Case Rep. 2016 Sep 2;2016:bcr2016216520. doi: 10.1136/bcr-2016-216520.

本文引用的文献

1
Cardiovascular manifestations of hypereosinophilic syndromes.嗜酸性粒细胞增多综合征的心血管表现。
Immunol Allergy Clin North Am. 2007 Aug;27(3):457-75. doi: 10.1016/j.iac.2007.07.001.
2
Hypereosinophilic syndrome: case presentation and update.高嗜酸性粒细胞综合征：病例报告与进展
J Allergy Clin Immunol. 2004 Jan;113(1):50-8. doi: 10.1016/j.jaci.2003.10.051.
3
Churg-Strauss syndrome with critical endomyocardial fibrosis: 10 year survival after combined surgical and medical management.伴有严重心内膜心肌纤维化的变应性肉芽肿性血管炎：手术与药物联合治疗后的10年生存率
Heart. 2002 May;87(5):E5. doi: 10.1136/heart.87.5.e5.
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Hypereosinophilic syndrome and restrictive cardiomyopathy due to apical thrombi.
Circulation. 2001 Jul 10;104(2):E3-4. doi: 10.1161/01.cir.104.2.e3.
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Churg-Strauss syndrome complicated by eosinophilic endomyocarditis.变应性肉芽肿性血管炎合并嗜酸性粒细胞性心内膜炎。
Mayo Clin Proc. 2000 Jun;75(6):631-5. doi: 10.4065/75.6.631.
6
The American College of Rheumatology 1990 criteria for the classification of Churg-Strauss syndrome (allergic granulomatosis and angiitis).美国风湿病学会1990年变应性肉芽肿性血管炎（Churg-Strauss综合征）分类标准。
Arthritis Rheum. 1990 Aug;33(8):1094-100. doi: 10.1002/art.1780330806.