Stefaniak Jerzy, Paul Małgorzata, Kacprzak Elzbieta, Polański Jerzy, Chomicz Lidia, Myjak Przemysłlaw
Katedra i Klinika Chorób Tropikalnych i Pasozytniczych, Akademia Medyczna, Poznań.
Wiad Parazytol. 2004;50(3):447-54.
Recent epidemiological reports have shown an increasing risk of E. multilocularis infection among red foxes and humans in Poland. The aims of the study were: (i) to improve the early detection of alveolar echinococcosis (AE) in humans by implementation of clinical, imaging, immunodiagnostic, ultrastructural and molecular methods, (ii) to realize the parasitological verification of registered cases suspected of alveococcosis by the specialized, parasitological centres, and (iii) to standardize diagnostic and therapeutic procedures for this severe parasitic disease. Since 1993, eight cases of AE were registered in the Poznań centre. The final diagnosis was based on PAS-positive staining of lesions by histopathology or a detection of the parasite's DNA in liver sections. Collaboration with physicians of various medical specialities is crucial for an early and more effective recognition of AE. Alveococcosis should always be considered in the differential diagnosis of space-occupying lesions in the liver suggesting slow-growing cancer.
近期的流行病学报告显示，在波兰，赤狐和人类感染多房棘球绦虫的风险不断增加。本研究的目的是：（i）通过实施临床、影像学、免疫诊断、超微结构和分子方法，改善人类肺泡型包虫病（AE）的早期检测；（ii）由专业寄生虫学中心对疑似肺泡型包虫病的登记病例进行寄生虫学验证；（iii）规范这种严重寄生虫病的诊断和治疗程序。自1993年以来，波兹南中心登记了8例AE病例。最终诊断基于组织病理学对病变进行的PAS阳性染色或在肝切片中检测到寄生虫的DNA。与各医学专科的医生合作对于早期更有效地识别AE至关重要。在鉴别诊断提示为生长缓慢的癌症的肝脏占位性病变时，应始终考虑肺泡型包虫病。
