用于全球公共卫生的微流控诊断技术。

Microfluidic diagnostic technologies for global public health.

作者信息

Yager Paul, Edwards Thayne, Fu Elain, Helton Kristen, Nelson Kjell, Tam Milton R, Weigl Bernhard H

机构信息

Department of Bioengineering, Box 355061, University of Washington, Seattle, Washington 98195, USA.

出版信息

Nature. 2006 Jul 27;442(7101):412-8. doi: 10.1038/nature05064.

DOI:10.1038/nature05064

PMID:16871209

Abstract

The developing world does not have access to many of the best medical diagnostic technologies; they were designed for air-conditioned laboratories, refrigerated storage of chemicals, a constant supply of calibrators and reagents, stable electrical power, highly trained personnel and rapid transportation of samples. Microfluidic systems allow miniaturization and integration of complex functions, which could move sophisticated diagnostic tools out of the developed-world laboratory. These systems must be inexpensive, but also accurate, reliable, rugged and well suited to the medical and social contexts of the developing world.

摘要

发展中世界无法获得许多最先进的医学诊断技术；这些技术是为有空调的实验室、化学试剂的冷藏储存、校准物和试剂的持续供应、稳定的电力、训练有素的人员以及样本的快速运输而设计的。微流体系统实现了复杂功能的小型化和集成化，这有望将精密诊断工具带出发达世界的实验室。这些系统必须价格低廉，但也要准确、可靠、坚固耐用，并且非常适合发展中世界的医疗和社会环境。