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美国老年人严重听力和记忆障碍之间的共病情况及风险因素。

Comorbidity between and risk factors for severe hearing and memory impairment in older Americans.

作者信息

Li Yanfeng, Healy Eric W, Drane J Wanzer, Zhang Jian

机构信息

Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC 29208, USA.

出版信息

Prev Med. 2006 Nov;43(5):416-21. doi: 10.1016/j.ypmed.2006.06.014. Epub 2006 Jul 28.

Abstract

OBJECTIVE

Comorbidities complicate our understanding of impairments and their risk factors. The objective of the current study was to assess the comorbidity between hearing impairment (HI) and memory impairment (MI) in older Americans and to assess to what extent they share common risk factors.

METHOD

Data were examined from 5252 participants aged 65 years or older from the Third National Health and Nutrition Examination Survey (1988-1994).

RESULTS

The prevalence of HI and MI was 21.4 (SE 0.8)% and 8.3 (0.6)%, respectively, but the prevalence of concurrent impairment was only 2.1 (0.2)%. African Americans had higher odds of MI than whites (OR=3.75, 95% CI: 2.81, 5.00), but not of HI (OR=0.62, 95% CI: 0.42, 0.91). Leisure physical activity was associated with lower odds of MI, good lung function was associated with lower odds of HI, and moderate alcohol use was associated with lower odds of both HI and MI. Compared with individuals free of HI, the OR of MI was 1.07 (95% CI: 0.78, 1.47) for individuals with HI.

CONCLUSION

Although prevalence was relatively high, comorbidity was surprisingly low, and the two impairments were not significantly associated. In addition to age, other factors appear to play critical but different roles in the development of these impairments.

摘要

目的

合并症使我们对损伤及其风险因素的理解变得复杂。本研究的目的是评估美国老年人听力障碍(HI)和记忆障碍(MI)之间的合并症情况,并评估它们在多大程度上共享共同的风险因素。

方法

对来自第三次全国健康和营养检查调查(1988 - 1994年)的5252名65岁及以上参与者的数据进行了检查。

结果

HI和MI的患病率分别为21.4(标准误0.8)%和8.3(0.6)%,但同时存在这两种损伤的患病率仅为2.1(0.2)%。非裔美国人患MI的几率高于白人(比值比=3.75,95%置信区间:2.81,5.00),但患HI的几率并非如此(比值比=0.62,95%置信区间:0.42,0.91)。休闲体育活动与较低的MI几率相关,良好的肺功能与较低的HI几率相关,适度饮酒与较低的HI和MI几率相关。与无HI的个体相比,有HI个体患MI的比值比为1.07(95%置信区间:0.78,1.47)。

结论

尽管患病率相对较高,但合并症出奇地低,且这两种损伤没有显著关联。除了年龄之外,其他因素似乎在这些损伤的发生发展中起着关键但不同的作用。

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