Stein D S, Stevens L M
Max-Planck-Institut für Entwicklungsbiologie, Tübingen, Germany.
Curr Opin Genet Dev. 1991 Aug;1(2):247-54. doi: 10.1016/s0959-437x(05)80078-4.
Dorsal-ventral and terminal pattern formation in the Drosophila embryo is mediated via inductive signals originating during oogenesis from the somatic follicle cells that ensheath the developing oocyte. This somatically expressed spatial information controls dorsal-ventral development by defining the polarity of a signal transduction pathway that results in the graded nuclear concentration of the dorsal gene product, a transcription factor.
果蝇胚胎的背腹和末端模式形成是通过卵母细胞发生过程中源自包裹发育中卵母细胞的体细胞滤泡细胞的诱导信号介导的。这种体细胞表达的空间信息通过定义一个信号转导途径的极性来控制背腹发育，该信号转导途径导致背基因产物（一种转录因子）的核浓度呈梯度变化。
