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人隐孢子虫、猫隐孢子虫和火鸡隐孢子虫中小双链RNA分子的特性分析

Characterisation of small double stranded RNA molecule in Cryptosporidium hominis, Cryptosporidium felis and Cryptosporidium meleagridis.

作者信息

Leoni Francesca, Gallimore Chris I, Green Jonathan, McLauchlin Jim

机构信息

Health Protection Agency Centre for Infections, London, UK.

出版信息

Parasitol Int. 2006 Dec;55(4):299-306. doi: 10.1016/j.parint.2006.06.006. Epub 2006 Aug 2.

Abstract

Coding regions of double stranded RNA molecules from 3 human faecal samples containing Cryptosporidium hominis, C. felis and C. meleagridis were characterised by sequencing and compared with that previously obtained for C. parvum. Sequences outside the coding regions were also obtained. Overall similarities of between 86% and 92% and between 86% and 93% were observed in the nucleotide and amino acid sequences respectively between these species. These larger sequences will allow further molecular tools for detection, identification and characterisation of Cryptosporidium spp.

摘要

对来自3份含有微小隐孢子虫、猫隐孢子虫和火鸡隐孢子虫的人类粪便样本的双链RNA分子编码区进行测序表征,并与先前获得的微小隐孢子虫编码区进行比较。还获得了编码区以外的序列。这些物种之间的核苷酸序列和氨基酸序列总体相似度分别为86%至92%和86%至93%。这些更长的序列将为隐孢子虫属的检测、鉴定和表征提供更多分子工具。

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