Fujita Yukihiro, Hara Yasushi, Ochi Hiroki, Nezu Yoshinori, Harada Yasuji, Yogo Takuya, Orima Hiromitsu, Tagawa Masahiro
Division of Veterinary Surgery, Department of Veterinary Science, Faculty of Veterinary Medicine, Nippon Veterinary and Life Science University, Japan.
J Vet Med Sci. 2006 Jul;68(7):675-9. doi: 10.1292/jvms.68.675.
The purpose of this study was to determine factors correlated with the severity of radiographic osteoarthritis (OA) scoring in dogs with cranial cruciate ligament rupture (CrCLR). Three radiographs of stifle joints (craniocaudal, mediolateral, and mediolateral radiograph with 90 degree flexion of the stifle and tarsal joints) were obtained from 36 dogs with CrCLR (Clinical group) and from 22 dogs without stifle joint disease (Control group). Information about these dogs was collected from the owners and from medical records. Radiographic OA scores in each dog in the clinical group were determined from radiographs using a numeric grading system previously reported. The tibial plateau angle (TPA) in each dog in both groups was measured on mediolateral radiographs with 90 degree flexion of the stifle and tarsal joints. The Mann-Whitney's U test was used for comparing variables between the clinical group and the control group, and Spearman's rank correlation test was used for evaluating correlations between radiographic OA scores and variables in the clinical group. No significant differences were detected between the clinical group and the control group for any of the variables. There were two positive correlations; one between the radiographic OA score and TPA (r=0.395, p=0.014); and the other between body weight and OA score (r=0.399, p=0.013) in the clinical group. Our results indicate that body weight and TPA could affect the severity of the radiographic OA score in dogs with CrCLR.
本研究的目的是确定与颅交叉韧带断裂（CrCLR）犬的放射学骨关节炎（OA）评分严重程度相关的因素。从36只患有CrCLR的犬（临床组）和22只无 stifle关节疾病的犬（对照组）获取了 stifle关节的三张X光片（前后位、内外侧位以及 stifle和跗关节屈曲90度时的内外侧位X光片）。从犬主和病历中收集了这些犬的信息。临床组中每只犬的放射学OA评分通过使用先前报道的数字分级系统从X光片中确定。两组中每只犬的胫骨平台角（TPA）在 stifle和跗关节屈曲90度的内外侧位X光片上进行测量。使用Mann-Whitney U检验比较临床组和对照组之间的变量，使用Spearman等级相关检验评估临床组中放射学OA评分与变量之间的相关性。在任何变量上，临床组和对照组之间均未检测到显著差异。临床组中有两个正相关；一个是放射学OA评分与TPA之间（r = 0.395，p = 0.014）；另一个是体重与OA评分之间（r = 0.399，p = 0.013）。我们的结果表明，体重和TPA可能会影响患有CrCLR的犬的放射学OA评分的严重程度。
