嗅周皮质损伤会损害同时性而非连续性特征阳性辨别学习。
Perirhinal cortex lesions impair simultaneous but not serial feature-positive discrimination learning.
作者信息
Campolattaro Matthew M, Freeman John H
机构信息
Department of Psychology, University of Iowa, Iowa City, IA 52242, USA.
出版信息
Behav Neurosci. 2006 Aug;120(4):970-5. doi: 10.1037/0735-7044.120.4.970.
Abstract
The role of the perirhinal cortex in discriminative eyeblink conditioning was examined by means of feature-positive discrimination procedures with simultaneous (A-/XA+) and serial (A-/X-->A+) stimulus compounds. Lesions of the perirhinal cortex severely impaired acquisition of simultaneous feature-positive discrimination but produced no impairment in serial feature-positive discrimination. The results suggest that the perirhinal cortex plays a role in discriminative eyeblink conditioning by resolving ambiguity in discriminations with overlapping stimulus elements.
摘要
通过同时呈现（A-/XA+）和序列呈现（A-/X-->A+）刺激复合物的特征阳性辨别程序，研究了嗅周皮质在辨别性眨眼条件反射中的作用。嗅周皮质损伤严重损害了同时性特征阳性辨别的习得，但对序列性特征阳性辨别没有损害。结果表明，嗅周皮质通过解决具有重叠刺激元素的辨别中的模糊性，在辨别性眨眼条件反射中发挥作用。
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2
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Behav Neurosci. 2005 Feb;119(1):190-201. doi: 10.1037/0735-7044.119.1.190.
3
In search of memory traces.
Annu Rev Psychol. 2005;56:1-23. doi: 10.1146/annurev.psych.56.091103.070239.
4
Interaction between perirhinal and medial prefrontal cortex is required for temporal order but not recognition memory for objects in rats.
J Neurosci. 2004 May 12;24(19):4596-604. doi: 10.1523/JNEUROSCI.5517-03.2004.
5
Recognition memory for complex visual discriminations is influenced by stimulus interference in rodents with perirhinal cortex damage.
Learn Mem. 2003 Nov-Dec;10(6):525-30. doi: 10.1101/lm.64503.
6
Long-term retention of the classically conditioned eyeblink response in rats.
Behav Neurosci. 2003 Aug;117(4):871-5. doi: 10.1037/0735-7044.117.4.871.
7
Impairments in visual discrimination after perirhinal cortex lesions: testing 'declarative' vs. 'perceptual-mnemonic' views of perirhinal cortex function.
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10
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