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嗅周皮质损伤会损害同时性而非连续性特征阳性辨别学习。

Perirhinal cortex lesions impair simultaneous but not serial feature-positive discrimination learning.

作者信息

Campolattaro Matthew M, Freeman John H

机构信息

Department of Psychology, University of Iowa, Iowa City, IA 52242, USA.

出版信息

Behav Neurosci. 2006 Aug;120(4):970-5. doi: 10.1037/0735-7044.120.4.970.

DOI:10.1037/0735-7044.120.4.970
PMID:16893302
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2556364/
Abstract

The role of the perirhinal cortex in discriminative eyeblink conditioning was examined by means of feature-positive discrimination procedures with simultaneous (A-/XA+) and serial (A-/X-->A+) stimulus compounds. Lesions of the perirhinal cortex severely impaired acquisition of simultaneous feature-positive discrimination but produced no impairment in serial feature-positive discrimination. The results suggest that the perirhinal cortex plays a role in discriminative eyeblink conditioning by resolving ambiguity in discriminations with overlapping stimulus elements.

摘要

通过同时呈现（A-/XA+）和序列呈现（A-/X-->A+）刺激复合物的特征阳性辨别程序，研究了嗅周皮质在辨别性眨眼条件反射中的作用。嗅周皮质损伤严重损害了同时性特征阳性辨别的习得，但对序列性特征阳性辨别没有损害。结果表明，嗅周皮质通过解决具有重叠刺激元素的辨别中的模糊性，在辨别性眨眼条件反射中发挥作用。

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本文引用的文献

1
Perirhinal cortex lesions impair feature-negative discrimination.嗅周皮层损伤会损害特征负性辨别能力。
Neurobiol Learn Mem. 2006 Sep;86(2):205-13. doi: 10.1016/j.nlm.2006.03.001. Epub 2006 Apr 17.
2
Purkinje cell loss by OX7-saporin impairs excitatory and inhibitory eyeblink conditioning.OX7-皂草素导致的浦肯野细胞损失会损害兴奋性和抑制性眨眼条件反射。
Behav Neurosci. 2005 Feb;119(1):190-201. doi: 10.1037/0735-7044.119.1.190.
3
In search of memory traces.寻找记忆痕迹。
Annu Rev Psychol. 2005;56:1-23. doi: 10.1146/annurev.psych.56.091103.070239.
4
Interaction between perirhinal and medial prefrontal cortex is required for temporal order but not recognition memory for objects in rats.大鼠对物体的时间顺序记忆需要鼻周皮质与内侧前额叶皮质之间的相互作用，但识别记忆则不需要。
J Neurosci. 2004 May 12;24(19):4596-604. doi: 10.1523/JNEUROSCI.5517-03.2004.
5
Recognition memory for complex visual discriminations is influenced by stimulus interference in rodents with perirhinal cortex damage.复杂视觉辨别任务的识别记忆受内嗅皮质受损啮齿动物的刺激干扰影响。
Learn Mem. 2003 Nov-Dec;10(6):525-30. doi: 10.1101/lm.64503.
6
Long-term retention of the classically conditioned eyeblink response in rats.大鼠经典条件性眨眼反应的长期保持
Behav Neurosci. 2003 Aug;117(4):871-5. doi: 10.1037/0735-7044.117.4.871.
7
Impairments in visual discrimination after perirhinal cortex lesions: testing 'declarative' vs. 'perceptual-mnemonic' views of perirhinal cortex function.嗅周皮层损伤后视觉辨别能力的损害：检验关于嗅周皮层功能的“陈述性”与“知觉记忆性”观点
Eur J Neurosci. 2003 Feb;17(3):649-60. doi: 10.1046/j.1460-9568.2003.02475.x.
8
Medial dorsal thalamic lesions impair blocking and latent inhibition of the conditioned eyeblink response in rats.
Behav Neurosci. 2002 Apr;116(2):276-85. doi: 10.1037//0735-7044.116.2.276.
9
Neuronal correlates of conditioned inhibition of the eyeblink response in the anterior interpositus nucleus.前间位核中眨眼反应条件性抑制的神经元关联
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10
Perirhinal cortex resolves feature ambiguity in complex visual discriminations.嗅周皮质解决复杂视觉辨别中的特征模糊问题。
Eur J Neurosci. 2002 Jan;15(2):365-74. doi: 10.1046/j.0953-816x.2001.01851.x.