Groisman Eduardo A, Mouslim Chakib
Department of Molecular Microbiology, Washington University School of Medicine, Campus P.O. Box 8230, 660 South Euclid Avenue, St. Louis, Missouri 63110, USA.
Nat Rev Microbiol. 2006 Sep;4(9):705-9. doi: 10.1038/nrmicro1478. Epub 2006 Aug 7.
Free-living organisms have the ability to gauge their surroundings and modify their gene expression patterns in ways that help them cope with new environments. Here we discuss the physiological significance of recent reports describing the ability of the Salmonella typhimurium PhoP/PhoQ two-component system to recognize and respond to host-derived antimicrobial peptides.
自由生活的生物体有能力感知周围环境，并以有助于它们应对新环境的方式改变其基因表达模式。在此，我们讨论近期报告中描述鼠伤寒沙门氏菌PhoP/PhoQ双组分系统识别并响应宿主来源抗菌肽能力的生理学意义。
