Pacheco-Sanchez Maribel, Boutin Yvan, Angers Paul, Gosselin André, Tweddell Russell J
Centre de recherche en horticulture, Pavilion de l'Envirotron, Université Laval, Quebec QC, G1K 7P4 Canada
Mycologia. 2006 Mar-Apr;98(2):180-5. doi: 10.3852/mycologia.98.2.180.
Polysaccharides from higher Basidiomycete mushrooms, mainly beta-D-glucans, are considered to be potent bioactive fungal compounds. In this study a beta-glucan (1.237 x 10(6) Da) consisting of (1-->3) and (1-->4) glucosidic linkages, named Collybia dryophila polysaccharide (CDP), was extracted from the wild mushroom C. dryophila. CDP was shown to strongly inhibit nitric oxide production in activated macrophages suggesting that this polysaccharide displays a potential anti-inflammatory activity. In addition it was shown that polysaccharides similar to CDP (CDP-like) are present in Lentinus edodes and different wild mushrooms collected in northeastern North America.
来自高等担子菌蘑菇的多糖，主要是β-D-葡聚糖，被认为是具有强大生物活性的真菌化合物。在本研究中，从野生蘑菇干小皮伞中提取了一种由（1→3）和（1→4）糖苷键组成的β-葡聚糖（1.237×10⁶ Da），命名为干小皮伞多糖（CDP）。结果表明，CDP能强烈抑制活化巨噬细胞中一氧化氮的产生，提示该多糖具有潜在的抗炎活性。此外，还表明香菇及在北美东北部采集的不同野生蘑菇中存在与CDP类似的多糖（类CDP）。
