Katz Dolly, Albalak Rachel, Wing J S, Combs V
Division of Tuberculosis Elimination, Centers for Disease Control and Prevention, 1600 Clifton Rd. NE, MS E10, Atlanta, GA 30333, USA.
Tuberculosis (Edinb). 2007 Jan;87(1):1-6. doi: 10.1016/j.tube.2005.12.003. Epub 2006 Aug 8.
Success in reducing tuberculosis (TB) incidence in developed nations has created a paradoxical problem for researchers. In many countries, there are too few cases to support the research necessary to maintain and accelerate the decline. We describe an approach to applied TB research that supports and focuses efforts of researchers at 21 academic, clinical, and governmental sites in two countries. The Tuberculosis Epidemiologic Studies Consortium (TBESC), funded by the Centers for Disease Control and Prevention (CDC) and by outside sources, conducts programmatically relevant epidemiologic, behavioral, economic, laboratory, and operational research for TB prevention and control. Our experience may serve as a model for other types of applied health care research.
发达国家在降低结核病发病率方面取得的成功给研究人员带来了一个自相矛盾的问题。在许多国家，病例数量过少，无法支持维持和加速发病率下降所需的研究。我们描述了一种应用于结核病研究的方法，该方法支持并聚焦于两个国家21个学术、临床和政府机构的研究人员的工作。由疾病控制与预防中心（CDC）和外部来源资助的结核病流行病学研究联盟（TBESC），针对结核病的预防和控制开展与项目相关的流行病学、行为学、经济学、实验室和运营研究。我们的经验可为其他类型的应用医疗保健研究提供借鉴。
