Heaney Robert P
Creighton University, Omaha, NE, USA.
Am J Clin Nutr. 2006 Aug;84(2):371-4. doi: 10.1093/ajcn/84.1.371.
Calcium intake in North America remains substantially below recommended amounts. Bottled waters high in calcium could help close that gap.
The objectives were to summarize and integrate published absorbability and biodynamic data concerning high-calcium mineral waters and to combine these data with hitherto unpublished analyses from my laboratory.
The usual library database was searched. The absorbability of calcium from a high-mineral water labeled with tracer quantities of (45)Ca was measured in human volunteers as a part of an otherwise low-calcium test meal. Published reports that used differing load sizes and meal conditions were harmonized by making corrections based on published calcium absorbability data.
All the high-calcium mineral waters had absorbabilities equal to milk calcium or slightly better. When tested, all produced biodynamic responses indicative of absorption of appreciable quantities of calcium (ie, increased urinary calcium, decreased serum parathyroid hormone, decreased bone resorption biomarkers, and protection of bone mass).
High-calcium mineral waters could provide useful quantities of bioavailable calcium.
北美的钙摄入量仍远低于推荐量。钙含量高的瓶装水有助于缩小这一差距。
总结并整合已发表的关于高钙矿泉水的吸收性和生物动力学数据,并将这些数据与我实验室迄今未发表的分析结果相结合。
检索了常用的图书馆数据库。作为低钙测试餐的一部分,在人类志愿者中测量了标记有微量(45)Ca的高矿物质水中钙的吸收性。通过根据已发表的钙吸收性数据进行校正,对使用不同负荷量和膳食条件的已发表报告进行了统一。
所有高钙矿泉水的吸收性与牛奶钙相当或略好。经测试,所有高钙矿泉水均产生了表明吸收了大量钙的生物动力学反应(即尿钙增加、血清甲状旁腺激素降低、骨吸收生物标志物降低以及对骨量的保护)。
高钙矿泉水可以提供大量可生物利用的钙。