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[脊椎椎间盘炎的外科治疗。78例分析]

[Surgical management of spondylodiscitis. An analysis of 78 cases].

作者信息

Frangen T M, Kälicke T, Gottwald M, Andereya S, Andress H-J, Russe O J, Müller E J, Muhr G, Schinkel C

机构信息

Chirurgische Klinik und Poliklinik, BG-Kliniken Bergmannsheil, Ruhr-Universität Bochum, Bürkle-de-la-Camp-Platz 1, 44789 Bochum.

出版信息

Unfallchirurg. 2006 Sep;109(9):743-53. doi: 10.1007/s00113-006-1084-7.

Abstract

Spondylodiscitis is a rare bacterial infection of the spine with an inflammatory, destructive course. To obtain further information on the therapeutic management and clinical course of spondylodiscitis, we retrospectively investigated 78 patients after surgical intervention. Mean age was 64 years (+/-4.6 years; range 21-80 years), the mean length of stay 49 days (+/-8.2 days; 3-121 days) including 24 days (+/-4.7 days; 0-112 days) in ICU. In hospital mortality was 9%. The cervical spine was affected in 10%, the thoracic spine in 35% and the lumbar/sacral spine in 55% of patients. Abscess formation occurred in 65% and destruction of the vertebral body in 74%. A total of 75% of patients presented with neurological deficits which could be improved by surgical intervention in 82% of cases. 24 patients were treated by ventral debridement and stabilization alone, 20 patients with a combined dorsoventral method. Most patients (n=34) were stabilized via dorsal bridging instrumentation without ventral debridement of the focus. Of this group, 23 patients were initially scheduled for secondary ventral debridement but complete healing was achieved prior to this, so further surgical therapy was unnecessary. Successful cure was obtained in 92% of cases. Based on our findings, we favor a split surgical approach: initially with dorsal internal fixation only. Abscesses can be drained percutaneously. Ventral debridement and stabilization is only recommended if insufficient stability can be obtained by dorsal fixation alone, as shown by the persistence of infection or pain.

摘要

脊椎椎间盘炎是一种罕见的脊柱细菌感染,病程呈炎症性、破坏性。为了获取有关脊椎椎间盘炎治疗管理和临床病程的更多信息,我们对78例接受手术干预后的患者进行了回顾性研究。平均年龄为64岁(±4.6岁;范围21 - 80岁),平均住院时间为49天(±8.2天;3 - 121天),其中在重症监护病房(ICU)的时间为24天(±4.7天;0 - 112天)。院内死亡率为9%。10%的患者颈椎受累,35%的患者胸椎受累,55%的患者腰椎/骶椎受累。65%的患者出现脓肿形成,74%的患者椎体破坏。共有75%的患者出现神经功能缺损,其中82%的病例通过手术干预得到改善。24例患者仅接受了前路清创和固定,20例患者采用了前后联合方法。大多数患者(n = 34)通过后路桥接器械固定而未进行病灶前路清创。在这组患者中,23例最初计划进行二期前路清创,但在此之前已实现完全愈合,因此无需进一步手术治疗。92%的病例获得了成功治愈。基于我们的研究结果,我们倾向于采用分步手术方法:最初仅进行后路内固定。脓肿可通过经皮引流。仅在仅通过后路固定无法获得足够稳定性(如感染或疼痛持续存在所示)时,才建议进行前路清创和固定。

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