Yirmiya Nurit, Gamliel Ifat, Shaked Michal, Sigman Marian
Department of Psychology, Hebrew University of Jerusalem, Mount Scopus, Jerusalem, 91905, Israel.
J Autism Dev Disord. 2007 Feb;37(2):218-29. doi: 10.1007/s10803-006-0163-5.
The cognitive and language skills of 30 siblings of children with autism (SIBS-A) and 30 siblings of typically developing children (SIBS-TD) were compared. Non-significant group differences emerged for cognition at both ages. At 24 months, significantly more SIBS-A demonstrated language scores one or two standard deviations below the mean compared to SIBS-TD. At 36 months, the groups differed significantly in receptive language, and more SIBS-A displayed receptive and expressive difficulties compared to SIBS-TD. Six SIBS-A (including one diagnosed with autism) revealed language scores more than two standard deviations below the mean at both ages, a pattern not seen in the SIBS-TD. Results are discussed in reference to language difficulties in autism spectrum disorders and the genetic liability for autism.
对30名自闭症儿童的兄弟姐妹（SIBS-A）和30名发育正常儿童的兄弟姐妹（SIBS-TD）的认知和语言技能进行了比较。两个年龄段的认知方面均未出现显著的组间差异。在24个月时，与SIBS-TD相比，显著更多的SIBS-A的语言得分比平均水平低一或两个标准差。在36个月时，两组在接受性语言方面存在显著差异，与SIBS-TD相比，更多的SIBS-A表现出接受性和表达性困难。六名SIBS-A（包括一名被诊断为自闭症的儿童）在两个年龄段的语言得分均比平均水平低两个以上标准差，这种模式在SIBS-TD中未出现。结合自闭症谱系障碍中的语言困难和自闭症的遗传易感性对结果进行了讨论。
