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宏基因组学:获取自然多样性的无尽途径。

Metagenomics: an inexhaustible access to nature's diversity.

作者信息

Langer Martin, Gabor Esther M, Liebeton Klaus, Meurer Guido, Niehaus Frank, Schulze Renate, Eck Jürgen, Lorenz Patrick

机构信息

BRAIN Aktiengesellschaft, Zwingenberg, Germany.

出版信息

Biotechnol J. 2006 Jul-Aug;1(7-8):815-21. doi: 10.1002/biot.200600111.

Abstract

The chemical industry has an enormous need for innovation. To save resources, energy and time, currently more and more established chemical processes are being switched to biotechnological routes. This requires white biotechnology to discover and develop novel enzymes, biocatalysts and applications. Due to a limitation in the cultivability of microbes living in certain habitats, technologies have to be established which give access to the enormous resource of uncultivated microbial diversity. Metagenomics promises to provide new and diverse enzymes and biocatalysts as well as bioactive molecules and has the potential to make industrial biotechnology an economic, sustainable success.

摘要

化学工业对创新有着巨大的需求。为了节省资源、能源和时间,目前越来越多既定的化学工艺正转向生物技术路线。这就要求白色生物技术去发现和开发新型酶、生物催化剂及应用。由于生活在某些生境中的微生物可培养性存在局限,必须建立能够获取未培养微生物多样性这一巨大资源的技术。宏基因组学有望提供新的、多样的酶和生物催化剂以及生物活性分子,并有可能使工业生物技术取得经济上的可持续成功。

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