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介入性肺辅助装置及其在急性呼吸窘迫综合征中的作用的最新进展。

An update on interventional lung assist devices and their role in acute respiratory distress syndrome.

作者信息

von Mach Marc-Alexander, Kaes Joachim, Omogbehin Babatunde, Sagoschen Ingo, Wiechelt Jascha, Kaiser Kristina, Sauer Oliver, Weilemann Ludwig Sacha

机构信息

II. Medical Department, University Hospitals, Langenbeckstr. 1, Mainz 55131, Germany.

出版信息

Lung. 2006 May-Jun;184(3):169-75. doi: 10.1007/s00408-005-2577-9.

Abstract

In recent years, pumpless arteriovenous systems for extracorporeal gas exchange have become a new therapeutic option for the treatment of patients suffering from acute respiratory failure. Experiences with the pumpless extracorporeal membrane lung in animal experiments and in patients with adult respiratory distress syndrome published in the current literature are reviewed. In addition this article presents a case of varicella pneumonia with persistent hypoxemia and hypercapnia under mechanical ventilation that showed a significant improvement with treatment with a pumpless extracorporeal lung assist using an arteriovenous shunt for eight days. The patient made a complete recovery. This is the first report of a patient with a life-threatening varicella pneumonia successfully treated with pumpless extracorporeal lung assist device. This review provides an update on interventional lung assist devices and a critical discussion of their advantages and limitations.

摘要

近年来,用于体外气体交换的无泵动静脉系统已成为治疗急性呼吸衰竭患者的一种新的治疗选择。本文综述了目前文献中关于无泵体外膜肺在动物实验和成人呼吸窘迫综合征患者中的应用经验。此外,本文还介绍了一例水痘肺炎患者,该患者在机械通气下持续低氧血症和高碳酸血症,使用动静脉分流的无泵体外肺辅助治疗8天后有显著改善。患者完全康复。这是首例使用无泵体外肺辅助装置成功治疗危及生命的水痘肺炎患者的报告。本综述提供了介入性肺辅助装置的最新信息,并对其优点和局限性进行了批判性讨论。

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