Salonia Andrea, Suardi Nazareno, Naspro Richard, Mazzoccoli Bruno, Zanni Giuseppe, Gallina Andrea, Bua Lina, Scattoni Vincenzo, Rigatti Patrizio, Montorsi Francesco
Department of Urology, University Vita-Salute San Raffaele, Scientific Institute San Raffaele Hospital, Milan, Italy.
Urology. 2006 Aug;68(2):302-6. doi: 10.1016/j.urology.2006.02.007.
To compare the cost of open transvesical prostatectomy (OP) with that of holmium laser enucleation (HoLEP) in the treatment of bladder outlet obstruction (BOO) attributed to benign prostatic hyperplasia.
From February to May 2004, 63 consecutive patients with symptomatic benign prostatic hyperplasia in a large prostate (70 to 220 g) and documented BOO were randomized to surgical treatment with OP (29 in group 1) or HoLEP (34 in group 2). All costs associated with the procedures during the hospital stay were recorded prospectively, and a cost-effectiveness analysis of the critical perioperative (ie, intraoperative and postoperative to hospital discharge) data was performed.
The cost analysis showed a mean perioperative cost of 2868.9 euros (3556.3 dollars) for group 1 and 2356.5 euros (2919.4 dollars) for group 2. A direct comparison analysis showed that the most significant cost factors were the operative time (average 16.1% and 25.1% to the cost of OP and HoLEP, respectively), operating room surgical setup/disposables, including laser fiber and resectoscope loop in group 2 (average 13.3% and 29.3% to the cost of OP and HoLEP, respectively), and length of postoperative hospital stay (average 53.3% and 32.0% to the cost of OP and HoLEP, respectively). Overall, the hospitalization cost of HoLEP was 9.6% less than that for OP.
Our data have demonstrated that HoLEP is associated with a significant hospital net cost savings compared with OP in patients undergoing surgery for symptomatic benign prostatic hyperplasia in large glands.
比较开放性经膀胱前列腺切除术(OP)与钬激光剜除术(HoLEP)治疗良性前列腺增生所致膀胱出口梗阻(BOO)的成本。
2004年2月至5月,63例有症状的大前列腺(70至220克)良性前列腺增生且有BOO记录的连续患者被随机分为接受OP手术治疗组(第1组29例)或HoLEP手术治疗组(第2组34例)。前瞻性记录住院期间与手术相关的所有费用,并对关键围手术期(即术中及术后至出院)数据进行成本效益分析。
成本分析显示,第1组围手术期平均成本为2868.9欧元(3556.3美元),第2组为2356.5欧元(2919.4美元)。直接比较分析表明,最显著的成本因素是手术时间(分别占OP和HoLEP成本的16.1%和25.1%)、手术室手术设置/一次性用品,包括第2组中的激光光纤和电切镜环(分别占OP和HoLEP成本的13.3%和29.3%)以及术后住院时间(分别占OP和HoLEP成本的53.3%和32.0%)。总体而言,HoLEP的住院成本比OP低9.6%。
我们的数据表明,对于因大腺体有症状的良性前列腺增生而接受手术的患者,与OP相比,HoLEP可显著节省医院净成本。