Homma Yukio, Yoshida Masaki, Seki Narihito, Yokoyama Osamu, Kakizaki Hidehiro, Gotoh Momokazu, Yamanishi Tomonori, Yamaguchi Osamu, Takeda Masayuki, Nishizawa Osamu
Department of Urology, Japan Red Cross Medical Center, Tokyo, Japan.
Urology. 2006 Aug;68(2):318-23. doi: 10.1016/j.urology.2006.02.042.
Overactive bladder (OAB) is a common symptom syndrome with urgency, urinary frequency, and urgency incontinence. To collectively express OAB symptoms, we developed the overactive bladder symptom score (OABSS).
Four symptoms--daytime frequency, nighttime frequency, urgency, and urgency incontinence--were scored. The weighing score was based on a secondary analysis of an epidemiologic database. Psychometric properties were examined in five patient groups: OAB (n = 83), asymptomatic controls (n = 34), stress incontinence (n = 29), benign prostatic hyperplasia (n = 28), and other diseases with urinary symptoms (n = 26).
The maximal score was defined as 2, 3, 5, and 5 for daytime frequency, nighttime frequency, urgency, and urgency incontinence, respectively. The sum score (OABSS 0 to 15) was significantly greater in the patients with OAB (8.36) than in the other patient groups (1.82 to 5.14). The distribution of the OABSS showed a clear separation between those with OAB and asymptomatic controls. The OABSS correlated positively with the individual scores (Spearman's r = 0.10 to 0.78) and quality-of-life scores assessed by the King's Health Questionnaire (Spearman's r = 0.20 to 0.49). The weighted kappa coefficients were 0.804 to 1.0 for each symptom score and 0.861 for OABSS. The posttreatment reduction in the OABSS was consistent with the global impression of patients of the therapeutic efficacy.
The OABSS, the sum score of four symptoms (daytime frequency, nighttime frequency, urgency, and urgency incontinence), has been developed and validated. OABSS may be a useful tool for research and clinical practice.
膀胱过度活动症（OAB）是一种常见的症状综合征，表现为尿急、尿频和急迫性尿失禁。为了综合表达OAB症状，我们制定了膀胱过度活动症症状评分（OABSS）。
对日间尿频、夜间尿频、尿急和急迫性尿失禁这四种症状进行评分。加权评分基于一个流行病学数据库的二次分析。在五组患者中检查了心理测量学特性：OAB患者（n = 83）、无症状对照组（n = 34）、压力性尿失禁患者（n = 29）、良性前列腺增生患者（n = 28）以及有泌尿系统症状的其他疾病患者（n = 26）。
日间尿频、夜间尿频、尿急和急迫性尿失禁的最高评分分别定义为2分、3分、5分和5分。OAB患者的总分（OABSS为0至15分）（8.36分）显著高于其他患者组（1.82至5.14分）。OABSS的分布显示OAB患者与无症状对照组之间有明显区分。OABSS与各个评分呈正相关（Spearman相关系数r = 0.10至0.78），与通过国王健康问卷评估的生活质量评分也呈正相关（Spearman相关系数r = 0.20至0.49）。每个症状评分的加权kappa系数为0.804至1.0，OABSS的加权kappa系数为0.861。治疗后OABSS的降低与患者对治疗效果的总体印象一致。
OABSS，即四种症状（日间尿频、夜间尿频、尿急和急迫性尿失禁）的总分，已经制定并得到验证。OABSS可能是研究和临床实践中的一个有用工具。
