Department of Urology, Graduate School of Medicine, The University of Tokyo, Japan.
BJU Int. 2009 Oct;104(7):968-72. doi: 10.1111/j.1464-410X.2009.08498.x. Epub 2009 Mar 10.
To assess the relationship between symptom severity and patient perceptions in patients with overactive bladder (OAB), as estimated by OAB Symptom Score (OABSS) and patient-reported outcome measures, respectively.
Post-hoc analyses were conducted on the existing data from patients with OAB. In addition to the OABSS, patients completed three patient-reported outcome measures, the OAB questionnaire (OAB-q), Patient Perception of Bladder Condition (PPBC) and Medical Outcomes Study Short-Form 36 (SF-36). Relationships of the OABSS were assessed through correlations with the OAB-q, PPBC and SF-36; all analyses were exploratory.
In all, 194 participants were analysed; the OABSS correlated relatively closely with the PPBC and OAB-q subscales of health-related quality of life (r = 0.36-0.57). There was a particularly good correlation with the OAB-q symptom bother (r = 0.73). However, the OABSS correlated somewhat less with the SF-36 subscales (r = 0.16-0.27). There were fairly close correlations between the OABSS and the OAB-q items; for daytime frequency with 'frequency of urination during daytime hours' (r = 0.44); night-time frequency with 'night-time urination' (r = 0.44), 'waking up at night because you had to urinate' (r = 0.51) and 'awakening from sleep' (r = 0.44); urgency with 'a sudden urge to urinate with little or no warning' (r = 0.65) and 'an uncontrollable urge to urinate' (r = 0.69), urgency incontinence with 'accidental loss of small amounts of urine' (r = 0.74) and 'urine loss associated with a strong desire to urinate' (r = 0.79). All the items except 'awakening from sleep' belonged to the OAB-q symptom bother domain.
It is possible to roughly but sufficiently infer patient perceptions of bladder condition and symptom bother by measuring symptom severity, as estimated by the OABSS.
通过分别使用膀胱过度活动症症状评分（OABSS）和患者报告的结局测量来评估膀胱过度活动症（OAB）患者的症状严重程度与患者感知之间的关系。
对 OAB 患者的现有数据进行了事后分析。除了 OABSS 之外，患者还完成了三个患者报告的结局测量，即 OAB 问卷（OAB-q）、患者对膀胱状况的感知（PPBC）和医疗结局研究 36 项简短量表（SF-36）。通过与 OAB-q、PPBC 和 SF-36 的相关性来评估 OABSS 的相关性；所有分析均为探索性分析。
共分析了 194 名参与者；OABSS 与 PPBC 和 OAB-q 健康相关生活质量子量表密切相关（r = 0.36-0.57）。与 OAB-q 症状困扰（r = 0.73）的相关性尤其好。然而，OABSS 与 SF-36 子量表的相关性稍低（r = 0.16-0.27）。OABSS 与 OAB-q 项目之间存在相当密切的相关性；日间频率与“日间排尿频率”（r = 0.44）；夜间频率与“夜间排尿”（r = 0.44）、“夜间因需要排尿而醒来”（r = 0.51）和“从睡眠中醒来”（r = 0.44）；急迫性与“突然有少量或无警告的排尿紧迫感”（r = 0.65）和“无法控制的排尿紧迫感”（r = 0.69），急迫性尿失禁与“少量尿液意外流失”（r = 0.74）和“与强烈排尿欲望相关的尿失禁”（r = 0.79）。除了“从睡眠中醒来”之外，所有项目均属于 OAB-q 症状困扰域。
通过测量 OABSS 估计的症状严重程度，大致但足够地推断出患者对膀胱状况和症状困扰的感知是有可能的。
