Chang Hyun Kyu, Bang Ki Tae, Lee Bo Han, Kim Jung Hyuk, Bae Kang Woo, Kim Myong Jin, Kim Seong-Kyu
Department of Internal Medicine, College of Medicine, Dankook University, Cheonan, Korea.
Korean J Intern Med. 2006 Jun;21(2):116-9. doi: 10.3904/kjim.2006.21.2.116.
A 40-year-old Korean man presented with painful swelling and tenderness of both ankle joints as well as the plantar surfaces of both feet, along with inflammatory back pain, and a purulent discharge from the urethral orifice. The patient also complained of sicca-like symptoms including dry eyes and dry mouth. An immunological analysis revealed a high titer of rheumatoid factor, positive results for antinuclear antibody and anti-Ro antibody, and a positive result for HLA-B27. An antibody titer for Chlamydia was also significantly increased. Positive results of the Schirmer's test and for keratoconjunctivitis sicca were confirmed by an ophthalmologist. These clinical manifestations were compatible with Chlamydia-induced reactive arthritis (ReA) accompanied by Sjögren's syndrome (SS). This is the first report of the combination of these two distinct disease entities in the Korean population.
一名40岁的韩国男性出现双踝关节以及双足底疼痛性肿胀和压痛，伴有炎性背痛，尿道口有脓性分泌物。患者还主诉有干眼症和口干等类似干燥综合征的症状。免疫分析显示类风湿因子滴度高、抗核抗体和抗Ro抗体结果呈阳性以及HLA - B27结果呈阳性。衣原体抗体滴度也显著升高。眼科医生证实了泪液分泌试验和干燥性角结膜炎结果呈阳性。这些临床表现符合衣原体诱导的反应性关节炎（ReA）伴干燥综合征（SS）。这是韩国人群中这两种不同疾病实体合并出现的首例报告。
