Smith A J, Hall D R, Grové D
Panorama Hospital, Cape Town, South Africa.
Int J Gynaecol Obstet. 2006 Dec;95(3):267-71. doi: 10.1016/j.ijgo.2006.07.003. Epub 2006 Aug 21.
To evaluate whether hormonal therapy (HT) had any significant effect on quality of life (QoL) in a selected group of postmenopausal women.
The study was conducted in a specialist private practice in Tygerberg, Cape Town, South Africa, over an 18-month period ending in July 2003. A questionnaire using the Utian Quality of Life (UQoL) scale was posted to all women with established postmenopausal status, seen over this period. 541 questionnaires were posted, 421 returned and 398 could be used. Women gave written informed consent.
The average age of the women was 60 years. 313 women (78.6%) were using hormone therapy (HT) while 275 women (69.1%) reported concomitant medical problems. HT users had significantly higher scores in three of the four QoL domains, namely, occupational (p=0.046), emotional (p=0.03), and sexual (p=0.009). There was no significant difference in the health domain (p=0.2).
This study found that post-menopausal South African women experienced that HT had a positive effect on global quality of life.
评估激素疗法（HT）对特定绝经后女性群体的生活质量（QoL）是否有显著影响。
该研究于南非开普敦泰格伯格的一家专科私人诊所进行，为期18个月，至2003年7月结束。在此期间，向所有已确定绝经状态的女性发放了一份使用尤田生活质量（UQoL）量表的问卷。共发放541份问卷，回收421份，其中398份可用。女性均签署了书面知情同意书。
女性的平均年龄为60岁。313名女性（78.6%）正在使用激素疗法（HT），而275名女性（69.1%）报告有伴随的医疗问题。HT使用者在四个生活质量领域中的三个领域得分显著更高，即职业领域（p = 0.046）、情感领域（p = 0.03）和性领域（p = 0.009）。健康领域无显著差异（p = 0.2）。
本研究发现，南非绝经后女性认为HT对总体生活质量有积极影响。
