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基于血管通路血流监测的质量改进项目对成本、通路闭塞和通路失败的影响。

Impact of a quality improvement programme based on vascular access flow monitoring on costs, access occlusion and access failure.

作者信息

Wijnen Edwin, Planken Nils, Keuter Xavier, Kooman Jeroen P, Tordoir Jan H M, de Haan Michiel W, Leunissen Karel M L, van der Sande Frank

机构信息

Department of Internal Medicine and Nephrology, University Hospital Maastricht, P. Debyelaan 25, 6202AZ Maastricht, Maastricht, The Netherlands.

出版信息

Nephrol Dial Transplant. 2006 Dec;21(12):3514-9. doi: 10.1093/ndt/gfl424. Epub 2006 Aug 18.

Abstract

BACKGROUND

Vascular access thrombosis is a substantial source of morbidity in chronic haemodialysis patients. Periodical access flow measurements can predict the presence of vascular access stenosis and provide an opportunity for early intervention to prevent subsequent vascular access thrombosis. By this system of quality improvement, vascular access-related costs might be reduced. The aim of this study was to analyse the cost impact of a quality improvement programme based on periodic access flow measurements.

METHODS

The number and costs of vascular access interventions (summary of angiography, percutaneous transluminal angioplasty, catheter placement, hospitalization days and costs for surgery) in the period 2001-2003 (quality improvement period; QIP, 218.6 patient-years observed) were retrospectively compared with a reference period (RP, 1996-1998, 214.4 patient-years observed) during which no access flow was measured. All access flow measurements were done on a regular base and interventions were performed according to the Kidney Disease Outcome Quality Initiative.

RESULTS

Surgical thrombectomy procedures were significantly less during the QIP (0.25 +/- 0.57 events/patient-year) compared with RP (0.63 +/- 1.06 events/patient-year; P = 0.000), whereas access loss was not significantly different. During the QIP, 205 radiological interventions were performed (0.88 +/- 1.16 events/patient-year), and in the RP around 48 (0.33 +/- 0.65 events/patient-year; P = 0.000). Access-related costs tended to be lower during the QIP compared with the RP. The cost reduction appeared to be limited to patients with arteriovenous graft (AVG), in which access-related costs were significantly lower during the QIP (2360.95 euro +/- 2838.17 euro patient-year) compared with the RP (4003.96 euro +/- 3810.92 euro patient-year; P = 0.012), but not in patients with arteriovenous fistula (AVF).

CONCLUSION

A quality improvement programme based on periodical access flow measurement reduced the number of acute vascular access failures due to thrombotic events and also significantly reduced health care costs in patients with AVG, but not in patients with AVF. The quality improvement programme had no effect on access survival.

摘要

背景

血管通路血栓形成是慢性血液透析患者发病的重要原因。定期进行通路血流量测量可预测血管通路狭窄的存在,并为早期干预提供机会,以预防随后的血管通路血栓形成。通过这种质量改进系统,可能会降低与血管通路相关的成本。本研究的目的是分析基于定期通路血流量测量的质量改进计划对成本的影响。

方法

回顾性比较2001 - 2003年期间(质量改进期;QIP,观察到218.6患者年)与参考期(RP,1996 - 1998年,观察到214.4患者年)血管通路干预的数量和成本(血管造影、经皮腔内血管成形术、导管置入、住院天数和手术成本的汇总),参考期内未测量通路血流量。所有通路血流量测量均定期进行,干预措施根据肾脏病预后质量倡议执行。

结果

与参考期相比,质量改进期手术取栓程序显著减少(0.25±0.57次事件/患者年),而参考期为(0.63±1.06次事件/患者年;P = 0.000),而通路丢失无显著差异。在质量改进期,进行了205次放射学干预(0.88±1.16次事件/患者年),而在参考期约为48次(0.33±0.65次事件/患者年;P = 0.000)。与参考期相比,质量改进期与通路相关的成本趋于降低。成本降低似乎仅限于动静脉移植物(AVG)患者,与参考期相比,质量改进期与通路相关的成本显著降低(2360.95欧元±2838.17欧元/患者年),而参考期为(4003.96欧元±3810.92欧元/患者年;P = 0.012),但动静脉内瘘(AVF)患者并非如此。

结论

基于定期通路血流量测量的质量改进计划减少了因血栓事件导致的急性血管通路失败的数量,并且显著降低了AVG患者的医疗成本,但对AVF患者无效。该质量改进计划对通路存活无影响。

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