Su Gang, Mao Binchen, Wang Jin
The State Key Laboratory of Pharmaceutical Biotechnology and Model Animal Institute, Department of Biochemistry, Nanjing University, Nanjing 210093, PR China.
In Silico Biol. 2006;6(4):307-10.
We have implemented a novel gapped-alignment algorithm to compare Position Frequency Matrices (PFMs) for Transcription Factor Binding Sites. The application compares an input PFM with those collected from public databases and outputs similarity scores, sequence alignments and related PFM clusters. MACO is freely accessible on a web server located at www.nicemice.cn/bioinfo/MACO. Source code is distributed upon request to the authors.
我们已经实现了一种新颖的带间隙比对算法，用于比较转录因子结合位点的位置频率矩阵（PFM）。该应用程序将输入的PFM与从公共数据库收集的PFM进行比较，并输出相似性得分、序列比对和相关的PFM簇。MACO可在位于www.nicemice.cn/bioinfo/MACO的网络服务器上免费访问。源代码可根据作者的要求提供。
