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与肉毒杆菌毒素注射相关的进行性颈椎后凸畸形。

Progressive cervical kyphosis associated with botulinum toxin injection.

作者信息

Hogan Kathleen A, Manning Erika L, Glaser John A

机构信息

Department of Orthopedic Surgery, Medical University of South Carolina, 96 Jonathan Lucas Street, Suite 708, Charleston, SC 29425, USA.

出版信息

South Med J. 2006 Aug;99(8):888-91. doi: 10.1097/01.smj.0000221627.12416.e1.

DOI:10.1097/01.smj.0000221627.12416.e1
PMID:16929888
Abstract

Weakness of the neck extensors can lead to "dropped head syndrome", a condition of progressive cervical kyphosis in which a patient is unable to hold their head up against the force of gravity. This condition can be associated with structural abnormalities of the spine as found in ankylosing spondylitis and vertebral fractures. Neuromuscular disorders, such as myasthenia gravis, muscular dystrophies, inflammatory myopathies, and motor neuron disorders such as amyotrophic lateral sclerosis (ALS) have also been reported as etiologies of dropped head syndrome. In this article, we describe an elderly woman with rapidly progressive cervical kyphosis following an injection of botulinum toxin A into her neck extensor musculature.

摘要

颈部伸肌无力可导致“低头综合征”,这是一种进行性颈椎后凸的病症,患者无法凭借自身力量抬头对抗重力。这种病症可能与强直性脊柱炎和椎体骨折等脊柱结构异常有关。神经肌肉疾病,如重症肌无力、肌肉萎缩症、炎性肌病,以及运动神经元疾病,如肌萎缩侧索硬化症(ALS),也被报道为低头综合征的病因。在本文中,我们描述了一名老年女性,在向其颈部伸肌注射A型肉毒杆菌毒素后出现了快速进展的颈椎后凸。

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