雅司病患者对 pertenue 密螺旋体和梅毒螺旋体 Nichols 株的免疫反应。

Immune response to Treponema pertenue and Treponema pallidum Nichols in patients with yaws.

作者信息

Martin P M, Cockayne A, Georges A J, Penn C W

机构信息

Institut Pasteur, Bangui.

出版信息

Res Microbiol. 1990 Feb;141(2):181-6. doi: 10.1016/0923-2508(90)90027-n.

DOI:10.1016/0923-2508(90)90027-n

PMID:1693218

Abstract

Human sera from African patients with acute yaws were analysed by Western blot (WB) against antigens of Treponema pallidum Nichols and two Treponema pertenue isolates. The Western blot patterns were remarkably similar from one patient to another, and strains of both subspecies exhibited exactly the same banding pattern. Sera from yaws patients failed to detect at least one antigen in T. pertenue which was absent from T. pallidum.

摘要

采用蛋白质印迹法（WB），以梅毒螺旋体Nichols株及两株 pertenue 亚种梅毒螺旋体的抗原为基础，对来自非洲急性雅司病患者的人血清进行分析。蛋白质印迹图谱在患者之间非常相似，两个亚种的菌株均呈现完全相同的条带模式。雅司病患者的血清未能检测到 pertenue 亚种梅毒螺旋体中至少一种梅毒螺旋体所没有的抗原。