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用于血小板和血浆病原体灭活的Mirasol PRT系统:现状与未来趋势综述

The Mirasol PRT system for pathogen reduction of platelets and plasma: an overview of current status and future trends.

作者信息

Goodrich Raymond P, Edrich Richard A, Li Junzhi, Seghatchian Jerard

机构信息

Navigant Biotechnologies Inc, Lakewood, CO 80215, USA.

出版信息

Transfus Apher Sci. 2006 Aug;35(1):5-17. doi: 10.1016/j.transci.2006.01.007. Epub 2006 Aug 28.

DOI:10.1016/j.transci.2006.01.007
PMID:16935562
Abstract

The safety of blood transfusion is still threatened by contamination of blood products with a variety of pathogens such as viruses, bacteria and parasites. A novel pathogen reduction process for platelets and plasma products, the Mirasol PRT system, has been developed and is under clinical evaluation for its efficacy and safety. The Mirasol PRT process is based on riboflavin photochemistry. This manuscript reviews current progress and future trends.

摘要

输血安全仍受到多种病原体(如病毒、细菌和寄生虫)污染血液制品的威胁。一种针对血小板和血浆制品的新型病原体灭活工艺——Mirasol PRT系统已被开发出来,目前正在对其有效性和安全性进行临床评估。Mirasol PRT工艺基于核黄素光化学原理。本文综述了当前的进展和未来趋势。

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