Goodrich Raymond P, Edrich Richard A, Li Junzhi, Seghatchian Jerard
Navigant Biotechnologies Inc, Lakewood, CO 80215, USA.
Transfus Apher Sci. 2006 Aug;35(1):5-17. doi: 10.1016/j.transci.2006.01.007. Epub 2006 Aug 28.
The safety of blood transfusion is still threatened by contamination of blood products with a variety of pathogens such as viruses, bacteria and parasites. A novel pathogen reduction process for platelets and plasma products, the Mirasol PRT system, has been developed and is under clinical evaluation for its efficacy and safety. The Mirasol PRT process is based on riboflavin photochemistry. This manuscript reviews current progress and future trends.
输血安全仍受到多种病原体(如病毒、细菌和寄生虫)污染血液制品的威胁。一种针对血小板和血浆制品的新型病原体灭活工艺——Mirasol PRT系统已被开发出来,目前正在对其有效性和安全性进行临床评估。Mirasol PRT工艺基于核黄素光化学原理。本文综述了当前的进展和未来趋势。