Ozdemir H, Karacorlu S A, Senturk F, Karacorlu M, Uysal O
Ophthalmology, The Istanbul Retina Institute Inc., Unimed Center, Istanbul, Turkey.
Eye (Lond). 2008 Feb;22(2):204-8. doi: 10.1038/sj.eye.6702563. Epub 2006 Aug 25.
To determine macular sensitivity and fixation characteristics in patients with unilateral resolved central serous chorioretinopathy (CSC) using fundus-related microperimetry.
We reviewed 15 eyes with resolved CSC and 15 normal healthy eyes that had undergone fundus-related microperimetry. The macular sensitivity was measured using the recently introduced fundus-related microperimeter, MP-1. The best-corrected visual acuity (VA) (BCVA), mean retinal sensitivity in the central 10 degrees (central microperimetry, cMP-1) and in the paracentral 10-20 degrees (paracentral microperimetry, pMP-1), and fixation stability and location were determined and compared with measurements in control eyes.
BCVA at the time of this study was 20/20 in all the affected eyes, and fundus examination and optical coherence tomography findings revealed no serous detachment. Eyes with CSC showed statistically significantly lower cMP-1 sensitivity and lower, but not significantly, pMP-1 sensitivity than control eyes (P<0.001, P=0.11, respectively). Eyes with CSC were not significantly different from control eyes in fixation location (P=1.00) or fixation stability (P=0.91). Fixation location was predominantly central in all eyes with CSC; fixation was stable in 12 (80%) and relatively unstable in 3 (20%).
Our study shows that eyes with resolved CSC can have lower retinal sensitivity in the central macula than control eyes, even after good VA has been obtained.
使用与眼底相关的微视野计确定单侧已消退的中心性浆液性脉络膜视网膜病变(CSC)患者的黄斑敏感性和注视特征。
我们回顾了15只已消退CSC的眼睛和15只接受过与眼底相关微视野计检查的正常健康眼睛。使用最近推出的与眼底相关的微视野计MP-1测量黄斑敏感性。测定最佳矫正视力(VA)(BCVA)、中心10度范围内的平均视网膜敏感性(中心微视野计,cMP-1)和旁中心10 - 20度范围内的平均视网膜敏感性(旁中心微视野计,pMP-1),以及注视稳定性和注视位置,并与对照眼的测量结果进行比较。
在本研究时,所有患眼的BCVA均为20/20,眼底检查和光学相干断层扫描结果显示无浆液性脱离。CSC患眼的cMP-1敏感性在统计学上显著低于对照眼,pMP-1敏感性低于对照眼但无显著差异(分别为P<0.001,P = 0.11)。CSC患眼在注视位置(P = 1.00)或注视稳定性(P = 0.91)方面与对照眼无显著差异。所有CSC患眼的注视位置主要在中心;12只(80%)注视稳定,3只(20%)相对不稳定。
我们的研究表明,即使获得了良好的视力,已消退CSC的患眼黄斑中心的视网膜敏感性仍可能低于对照眼。