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达托霉素对耐甲氧西林金黄色葡萄球菌(包括异质性糖肽类耐药菌株)的体外活性。

In vitro activity of daptomycin against methicillin-resistant Staphylococcus aureus, including heterogeneously glycopeptide-resistant strains.

作者信息

Diederen Bram M W, van Duijn Inge, Willemse Piet, Kluytmans Jan A J W

机构信息

Laboratory of Microbiology and Infection Control, Amphia Hospital, Breda, The Netherlands.

出版信息

Antimicrob Agents Chemother. 2006 Sep;50(9):3189-91. doi: 10.1128/AAC.00526-06.

Abstract

The purpose of the present study was to assess the in vitro activity of daptomycin against a well-defined collection of methicillin-resistant Staphylococcus aureus (MRSA) isolates (n = 98), including heterogeneously glycopeptide-resistant MRSA (hGISA) strains. Susceptibility testing was performed by using the Etest system. Daptomycin was potent against both glycopeptide-susceptible and hGISA strains.

摘要

本研究的目的是评估达托霉素对一组明确的耐甲氧西林金黄色葡萄球菌(MRSA)分离株(n = 98)的体外活性,其中包括异质性糖肽耐药MRSA(hGISA)菌株。采用Etest系统进行药敏试验。达托霉素对糖肽敏感菌株和hGISA菌株均有活性。

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