Donoso Alejandro F, Cruces Pablo I, Camacho Jorge F, León José A, Kong Jorge A
Pediatric Intensive Care Unit, Padre Hurtado Hospital, Santiago, Chile.
Pediatr Infect Dis J. 2006 Sep;25(9):846-8. doi: 10.1097/01.inf.0000232630.70138.a2.
Severe pertussis has a high mortality risk, especially in those with high white blood cell counts and pulmonary hypertension. Exchange transfusion can reduce the leukocyte mass in blood. We report 3 young infants with severe pertussis and hyperleukocytosis who developed cardiogenic shock and pulmonary hypertension. Exchange transfusion was performed. The white blood cell count decreased accompanied by improvement in the cardiopulmonary condition and survival in the 3 infants. Exchange transfusion should be considered in patients with severe pertussis with hyperleukocytosis.
重症百日咳有很高的死亡风险，尤其是在白细胞计数高和患有肺动脉高压的患者中。换血疗法可以减少血液中的白细胞数量。我们报告了3例患有重症百日咳和白细胞增多症的幼儿，他们出现了心源性休克和肺动脉高压。进行了换血疗法。3例婴儿的白细胞计数下降，同时心肺状况改善并存活。对于患有重症百日咳和白细胞增多症的患者，应考虑换血疗法。
