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野生小家鼠(Mus musculus)染色体上银染核仁组织区分布的变异。

Variation in the distribution of silver-staining nucleolar organizer regions on the chromosomes of the wild mouse, Mus musculus.

作者信息

Suzuki H, Kurihara Y, Kanehisa T, Moriwaki K

机构信息

National Institute of Genetics, Japan.

出版信息

Mol Biol Evol. 1990 May;7(3):271-82. doi: 10.1093/oxfordjournals.molbev.a040598.

Abstract

A silver staining method was used to analyze the distribution of nucleolar organizer regions (Ag-NORs) on chromosomes of 45 wild mice (Mus musculus). The four subspecies represented were M. m. musculus, M. m. molossinus, M. m. castaneus, and M. m. bactrianus. Ag-NORs were observed near the centromeric regions of 11 chromosomes (4, 8, 9, 10, 11, 12, 15, 16, 17, 18, and 19), indicating a preponderance of Ag-NORs on smaller chromosomes. The first five loci have not been observed previously. It is suggested that a correlation may exist between the specific features of mouse Ag-NORs and the events involved in intra- and interchromosomal homogenization of rDNA.

摘要

采用银染法分析了45只野生小家鼠(Mus musculus)染色体上核仁组织区(Ag-NORs)的分布情况。所代表的四个亚种分别是小家鼠指名亚种(M. m. musculus)、日本小家鼠(M. m. molossinus)、印度小家鼠(M. m. castaneus)和阿富汗小家鼠(M. m. bactrianus)。在11条染色体(4、8、9、10、11、12、15、16、17、18和19)的着丝粒区域附近观察到了Ag-NORs,这表明较小染色体上的Ag-NORs占优势。前五个位点此前尚未被观察到。有人提出,小鼠Ag-NORs的特定特征与rDNA染色体内部和染色体间均一化所涉及的事件之间可能存在相关性。

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