实验室动物痛苦问题工作组报告。

Report of the Working Group on Animal Distress in the Laboratory.

作者信息

Brown Marilyn, Carbone Larry, Conlee Kathleen M, Dawkins Marian S, Duncan Ian J, Fraser David, Griffin Gilly, Hampshire Victoria A, Lambert Lesley A, Mench Joy A, Morton David, Richmond Jon, Rollin Bernard E, Rowan Andrew N, Stephens Martin L, Würbel Hanno

机构信息

Charles River Laboratories Foundation, 251 Ballardvale Street, Wilmington, MA 01887, USA.

出版信息

Lab Anim (NY). 2006 Sep;35(8):26-30. doi: 10.1038/laban0906-26.

DOI:10.1038/laban0906-26

PMID:16943790

Abstract

Finding ways to minimize pain and distress in research animals is a continuing goal in the laboratory animal research field. Pain and distress, however, are not synonymous, and measures that alleviate one may not affect the other. Here, the authors provide a summary of a meeting held in February 2004 that focused on distress in laboratory animals. They discuss the difficulties associated with defining 'distress,' propose methods to aid in recognizing and alleviating distressful conditions, and provide recommendations for animal research conduct and oversight that would minimize distress experienced by laboratory animals.

摘要

寻找方法将实验动物的疼痛和痛苦降至最低，是实验动物研究领域的一个持续目标。然而，疼痛和痛苦并非同义词，减轻其中一种的措施可能不会影响另一种。在此，作者总结了2004年2月召开的一次会议，该会议聚焦于实验动物的痛苦。他们讨论了与定义“痛苦”相关的困难，提出了有助于识别和缓解痛苦状况的方法，并为动物研究的实施和监督提供了建议，这些建议将使实验动物所经历的痛苦降至最低。